The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Articles covered in this volume include Biological Activity and Biotechnological Aspects of Peptide Nucleic Acid (PNA); Changing Images of the Gene; Historical and Modern Genetics of Plant Graft Hybridization; Step into the Groove: Engineered Transcription Factors as Modulators of Gene Expression; Step Out of the Groove: Epigenetic Gene Control Systems and Engineered Transcription Factors.