Cancer Chemotherapy and Biotherapy Principles and Practice
Innbundet /
2010
/ Engelsk
Produktdetaljer
ISBN
9781605474311
Publisert
2010-11-16
Utgave
5. utgave
Utgiver
Vendor
Lippincott Williams And Wilkins
Vekt
2155 gr
Høyde
276 mm
Bredde
213 mm
Aldersnivå
06, P
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
848
Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents-their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations.This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised.A companion website includes the fully searchable text and an image bank.
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A comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, it provides information on various drugs and biological agents - their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance.
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Section 1: BASIC PRINCIPLES OF CANCER TREATMENT1: Clinical Strategies for Cancer Treatment: The Role of DrugsBruce Chabner2: Target Identification and Drug DiscoveryEd Sausville3: Clinical Drug Development and Approval for MarketingThomas Roberts4: Principles of PharmacokineticsJerry Collins5: Special Aspects of Brain Tumor ChemotherapyJeffrey Supko & Tracy Batchelor6: PharmacogeneticsHoward McLeod7: Barriers to Drug DeliveryBrendan CurtiSection 2: CYTOTOXIC AGENTS8: AntifolatesCarmen Allegra & Bruce Chabner9: Fluoro-pyrimidinesDavid Ryan, Bruce Chabner & Ray Wadlow10: Cytidine AnaloguesDavid Ryan & Bruce Chabner11: Purine AnaloguesKen Hande12: HydroxyureaBruce Chabner13: Antimitotic DrugsRoss Donehower14: Alkylating Agents (Including Methylating Agents)Stan Gerson & Henry Friedman15: Platinum AnaloguesEd Reed16: Antitumor Antibiotics (Including Bleomycin)Bruce Chabner17: Topoisomerase I InhibitorsAlex Spaareboom & William Zamboni18: Topoisomerase II Inhibitors: AnthracyclinesJim Doroshow19: Topoisomerase II Inhibitors: Etoposide, TeniposideGeorge Hartman & Yves Pommier20: L-AsparaginaseBruce Chabner & Alison FriedmannSection 3: MOLECULARLY TARGETED THERAPIES21: Proteosome InhibitorsOrhan Sezar22: HDAC InhibitorsSusan Bates23: Differentiating Agents (Retinoids)Bruce Chabner24: Arsenic TrioxideBruce Chabner25: Monoclonal Antibodies: Discovery & DevelopmentDavid Scheinberg26: Anti-angiogenic Agents (Including MonAB)William Gradishar & Kari Wisinski27: Anti-EGFR Therapies (Including MonAB)Lecia Sequist & Joel Neal28: Anti-her 2 TherapiesEric Winer29: Intracellular Signal Inhibitors (bcr-abl)Bruce Chabner & Jeffrey Barnes30: Signal Transduction Inhibitors in DevelopmentJeff Clark31: Inhibitors of the PI3k Pathway & Mitotic KinasePercy IvySection 4: IMMUNOLOGIC AGENTS32: Interferon and CytokinesDavid McDermott33: VaccinesRobert G. Fenton34: Adoptive Cellular TherapiesCassian Yee35: Immuno-modulatory Drugs (IMIDS, Anti-CTLA4)Paul Richardson et al.Section 5: HORMONAL THERAPY36: Hormonal Therapy of Breast CancerBeverly Moy & Paul Goss37: GNRH Agonists and Anti-AndrogensRichard LeeSection 6: SUPPORTIVE CARE38: Pain Management in Cancer PatientsPaul Glare39: Colony Stimulating FactorsGary Lyman40: Anti-nausea MedicationsIan Olver41: Bone Loss ModulatorsMatthew Smith42: Intravenous Access and Catheter ManagementRachel RosovskySection 7: SURVIVORSHIP43: Monitoring for Late Side Effects of ChemotherapyRichard Schilsky, Charles Erlichman & Brian Costello
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Produktdetaljer
ISBN
9781605474311
Publisert
2010-11-16
Utgave
5. utgave
Utgiver
Vendor
Lippincott Williams And Wilkins
Vekt
2155 gr
Høyde
276 mm
Bredde
213 mm
Aldersnivå
06, P
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
848