This third edition is the new, thoroughly revised edition of the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Previously titled _Cellular and Molecular Neurobiology_, the new title better reflects this focus. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field. While the book does cover the important facts, it also presents the background for how researchers arrived at this knowledge to provide a context for the field. It teaches not only how excitable cells work in detail, but also how to construct and conduct intelligent research experiments. This book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike. * 80% new or updated material * Fifteen appendices describing neurobiological techniques are interspersed in the text * Now in full color throughout, with more than 400 carefully selected and constructed illustrations * Provides an instructor website with all the images in electronic format, plus additional material