I. Biochemical Analysis of Metabolic Pathways.- Adenosine in Neurohumoral and Regulatory Roles in the Brain.- Lipid Metabolism and its Regulation in Brain Tissue.- Choline and its Metabolic Successors in Brain.- Structural and Functional Significance of Brain Glycoproteins.- Antimetabolic Action on the Pentose Phosphate Pathway in the Central Nervous System Induced by 6-Aminonicotinamide.- Studies of Flux Rates at the Glucose 6-Phosphate Crossover.- Purification and Regulation of Phosphate-Activated Pig Brain Glutaminase.- Functional Aspects of Nucleic Acid Metabolism in Brain.- Uptake and Action of Glycine in Cultures of Central Nervous Tissue from Rat.- Neuronal Activity and Axonal Flow.- Intra-Axonal Transport of Young Amine Granules: Implications for Nerve-Terminal Function.- The Application of Micromethods to Neurochemistry.- Serum as Medium for Brain and Other Tissues Respiring in vitro.- II. Membrane Function and Neurotransmission.- Importance of Structure and Organization for the Chemical Reactions in Excitable Membranes.- Allostery and Permeability of Cellular Membranes.- Release of 3H-Acetylcholine and 3H-Choline from the Cerebral Cortex of the Rat Following Administration of 3H-Choline.- Changes in the Enzymes for the Metabolism of Acetylcholine During Development of the Central Nervous System.- Acetylcholinesterase and Choline Acetyltransferase in Hippocampus after Various Septal Lesions in Rats.- Subcellular Localization of Glycosyl-Transferases in Synaptosomes and Mitodrondria of Brain.- Neurochemical Aspects of Behavior.- Histamine in the Brain: Importance of Transmethylation Processes and Their Regulation.- Macromolecular Organization of Membranes and Organelles in Nerve Tissue.- III. Hormonal and Pharmacological Studies.- Effects of Ergot DH-Alkaloids on the Metabolism and Function of the Brain. An Approach Based on Studies with DH-Ergonine.- Effect of Nicergoline on Some Ischemia-Induced Metabolic Changes in the Brain of Cat.- Interference of Neurologically Active Drugs with Metabolism of RNA in Brain.- Some Histochemical, Biochemical, and Pharmacological Aspects of Differentiation of Neuroblastoma Cells of Mouse.- Analogues of ACTH, Conditioned Avoidance Behaviour and Metabolism of Macromolecules in Brain of Rat.- Hypophysectomy and Metabolism of Brain Proteins.- Early Effects of Thyroxine and Reserpine on the Hypothalamic-Pituitary-Thyroid Axis of Young Rats.