Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail. Comprehensive protocols included for the study of * _In vitro _methods for studying neuroendocrine pulsatility * _In vivo_ sampling and recording procedures for monitoring pulsatility in several species * Improved quantitative and analytical methods for the study of hormone pulsatility