Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
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Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans.
Ch 1. An introduction to carbohydrate chemistry. Ch 2. Enzymes of glycosylation - the glycosyltransferases. Ch 3. Polysaccharides. Ch 4. N-linked glycoproteins. Ch 5. O-linked (mucin-type) glycoproteins. Ch 6. O-glcnac glycosylation of nuclear and cytosolic proteins. Ch 7. Species specific and unusual types of glycoprotein glycosylation. Ch 8. Glycoconjugates of the extracellular matrix of animals. Ch 9. Glycosphingolipids. Ch 10. Glycan chain extension and some common and important glycan structures. Ch 11. Sialic acids. Ch 12. Glycosylphosphatidylinositol (gpi)-anchored proteins. Ch 13. Carbohydrate-binding proteins (lectins). Ch 14. Tools for carbohydrate analysis. Ch 15. Modulation of glycan expression using inhibitors of N- and O-linked glycoconjugate processing, and transgenic technology. Ch 16. Disease processes in which carbohydrates are involved. Ch 17. Carbohydrate-based therapeutics. Ch18. Carbohydrate biotechnology.
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Produktdetaljer

ISBN
9781859960226
Publisert
2002-10-01
Utgiver
Vendor
Bios Scientific Publishers Ltd
Vekt
839 gr
Høyde
248 mm
Bredde
174 mm
Aldersnivå
UU, UP, P, 05, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
298

Biographical note

Dr SusanBrooks, Dr M Dwek, Udo Schumacher