First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time.
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1. Pharmacokinetic-Pharmacodynamic Modeling of Reversible Drug Effects J. Venitz 2. Pharmacokinetic-Pharmacodynamic Modeling of Irreversible Drug Effects S. Ebert 3. Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications J. Fleishaker and J. Ferry 4. Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling G. Hochhaus and H. Derendorf 5. Pharmacokinetic-Pharmacodynamic Correlations of Anesthetics Agents V.D. Schmith and K. Muir 6. Pharmacokinetic-Pharmacodynamic Correlations of Analgesics J.S. Walker 7. Pharmacokinetic-Pharmacodynamic Correlations of Benzodiazepines S.K. Gupta 8. Pharmacokinetic-Pharmacodynamic Correlations of Anticonvulsants M. Danhof and R. Voskuyl 9. Pharmacokinetic-Pharmacodynamic Correlations of Cardiovascular Drugs R. Lalonde 10. Pharmacokinetic-Pharmacodynamic Correlations of Selected Vasodilators T.-B. Tzeng and H.-L. Fung 11. Pharmacodynamics Correlations of Anticoagulants D. Mungall and R.H. White 12. Pharmacokinetic-Pharmacodynamic Correlations of Antihistamines E. Snoeck, A. Van Peer, and J. Heykants 13. B2-Agonists: Terbutaline, Albuterol, and Fenoterol G. Hochhaus and H. Mllmann 14. Pharmacokinetic-Pharmacodynamic Correlations of Corticosteriods H. Mllmann et al. 15. Pharmacokinetic-Pharmacodynamic Modeling of Antibiotics A.Nolting and H. Derendorf 16. Clinical Pharmacodynamics of Anticancer Drugs H.L. McLeod and W.E. Evans 17. Computer Applications in Clinical Pharmacokinetics and Pharmacodynamics D. Mungall, J. Heissler, and M. Kaltenbach
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Produktdetaljer

ISBN
9780367228033
Publisert
2019-06-12
Utgiver
Vendor
CRC Press
Vekt
454 gr
Høyde
254 mm
Bredde
178 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet

Biographical note

Hartmut Derendorf, Ph.D., is Professor and Chairman of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida. Gunther Hochhaus, Ph.D., is Associate Professor of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.