I. BASIC CELL PROCESSES: INTEGRATION AND COORDINATION Introduction to PhysiologyMolecular InteractionsCompartmentation: Cells and TissuesEnergy and Cellular MetabolismMembrane DynamicsCommunication, Integration, and Homeostasis II. HOMEOSTASIS AND CONTROL Introduction to the Endocrine SystemNeurons: Cellular and Network PropertiesThe Central Nervous SystemSensory PhysiologyEfferent Division: Autonomic and Somatic Motor ControlMusclesIntegrative Physiology I: Control of Body Movement III. INTEGRATION OF FUNCTION Cardiovascular PhysiologyBlood Flow and the Control of Blood PressureBloodMechanics of BreathingGas Exchange and TransportThe KidneysIntegrative Physiology II: Fluid and Electrolyte Balance IV. METABOLISM, GROWTH, AND AGING The Digestive SystemMetabolism and Energy BalanceEndocrine Control of Growth and MetabolismThe Immune SystemIntegrative Physiology III: ExerciseReproduction and Development

This title is a Pearson Global Edition. The editorial team at Pearson has worked closely with educators around the world to include content which is especially relevant to students outside the United States. Emphasize “big picture” biological concepts and the integrative nature of how organ systems work together ● EXPANDED! Easy-to-Follow Instructions help students integrate information by creating concept maps and flow charts. o ENHANCED! Figure 1.3 “Focus on...Mapping” now includes succinct hints, updated recommendations for creating electronic concept maps, and an illustrated 3-step example. o NEW! A Ready-to-Go Teaching Module provides extensive teaching suggestions for instructors to guide students in creating concept maps. o Mapping Exercises are included in the end-of-chapter Review Questions for most chapters. ● Unique Integrative Physiology chapters (Chapters 13, 20, and 25) ask students to step back and look at the big picture to learn how separate physiological processes work together in an integrated system. These chapters explore control of body movement, fluid and electrolyte balance, and exercise and demonstrate the emergent properties of the various body systems. ● Four core concepts in biology that are most related to physiology are introduced in Chapter 1, informed by recommendations from academic organizations including NSF, AAAS, HHMI, and AAMC. The four themes explore structure-function relationships, biological energy use, information flow within an organism, and homeostasis and control systems that maintain homeostasis. Guide students to think critically and use information to solve real-world problems ● NEW! “Try it” Activities present a realworld research problem or classic experiment and guide students in analyzing the data and thinking like a scientist by considering different outcomes, designing a follow-up experiment, or forming a hypothesis. “Try it” Activity topics include Graphing (Chapter 1), Cell Membrane Models (Chapter 5), Action Potentials in Venus Flytraps (Chapter 8), SaltySweet Taste Experiment (Chapter 10), the FrankStarling Law of the Heart (Chapter 14), Insulin (Chapter 19) and Oral Rehydration Therapy (Chapter 21). o NEW! An assignable version of each “Try it” activity is available in Mastering A&P, including coaching and feedback. ● UPDATED! Figure 1.15 “Focus on...Graphing” now integrates instructions and example graphs more closely to immediately engage students in active learning and concludes with the new “Try It” activity that students could complete in class or outside of class. o NEW! A Ready-to-Go Teaching Module includes a wealth of teaching ideas to help students build and practice graphing skills. ● Running Problems explore a real-world disease or disorder that unfolds in short segments throughout the chapter. Students can check their understanding by comparing their answers with those in Problem Conclusion at the end of each chapter. Related Running Problem Coaching Activities can be assigned in Mastering A&P. ● Questions throughout the chapter give students an opportunity to check their understanding. o Figure Questions and Graph Questions ask students to think critically and analytically, providing frequent stop-and-think opportunities to reinforce important concepts while building visualization and graphing skills. Answers to these questions appear at the end of the text, in Appendix A. o Concept Checks appear at intervals throughout the chapter and test students before they move on. &#

About the Book Emphasize “big picture” biological concepts and the integrative nature of how organ systems work together ● Expanded Easy-to-Follow Instructions help students integrate information by creating concept maps and flow charts. o Enhanced Figure 1.3 “Focus on...Mapping” now includes succinct hints, updated recommendations for creating electronic concept maps, and an illustrated 3-step example. o A Ready-to-Go Teaching Module provides extensive teaching suggestions for instructors to guide students in creating concept maps. Guide students to think critically and use information to solve real-world problems ● “Try it” Activities present a real-world research problem or classic experiment and guide students in analyzing the data and thinking like a scientist by considering different outcomes, designing a follow-up experiment, or forming a hypothesis. “Try it” Activity topics include Graphing (Chapter 1), Cell Membrane Models (Chapter 5), Action Potentials in Venus Flytraps (Chapter 8), Salty-Sweet Taste Experiment (Chapter 10), the Frank-Starling Law of the Heart (Chapter 14), Insulin (Chapter 19) and Oral Rehydration Therapy (Chapter 21). ● Updated Figure 1.15 “Focus on...Graphing” now integrates instructions and example graphs more closely to immediately engage students in active learning, and concludes with the new “Try It” activity that students could complete in class or outside of class. o A Ready-to-Go Teaching Module includes a wealth of teaching ideas to help students build and practice graphing skills. Cover the right balance of fundamental physiology concepts along with exciting research developments ● Carefully selected content updates have been added throughout the text to reflect the dynamic state of physiology research, including: o Developments using Induced Pluripotent Stem Cells (iPSs) o Updates on mechanisms of axonal transport and associated diseases: dynein, kinesin, fragile X, Alzheimer’s, and microcephaly o New information on the role of the kidney in hypertension o Extensive revisions in Chapter 24 on the Immune System, including 6 new figures and new discussions on long-lived plasma cells, mucosa-associated lymphoid tissue (MALT), self-antigens, negative selection, Zika virus, B cell receptors, regulatory T cells, and more. ● Updated Easy-to-follow references direct learners to related content and media o IP 2.0 integrated call-outs and Mastering Study Area references highlight practice opportunities and quizzes for students. o Learning Outcomes appear at the beginning of every chapter to provide a learning framework for students, allowing them to easily test their knowledge after reading. ● Background Basics and Concept Links help students locate, revisit, and review topics they encounter. ● Carefully developed Art program helps students learn physiology more efficiently. o Additional “Focus On...” Figures highlight the anatomy and physiology of important organs, including the skin, bone marrow, the liver, the spleen, the thymus gland, and the pineal gland. Pearson Mastering A&P is not included. Students, if Pearson Mastering A&P is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. Pearson Mastering A&P should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information. Guide students to think critically and use information to solve real-world problems