Characterization of Micro and Nanoparticles for Biomedical Applications is a helpful guide for industry researchers, academicians, regulatory experts and material scientists working in the field of pharmaceuticals, cosmeceuticals, nutraceuticals, agriculture, food, fragrance, and in the chemical industries. It aims to provide a one-stop resources on all the analytical techniques used in the field of micro and nanoparticles evaluation and characterization. The book's chapters bring together knowledge on current analytical methodologies, limitations and advances in the in vitro analysis field. Users from the equipment industry will benefit from its innovations by understanding the needs of researchers and the challenges of current techniques. With the expectation of "high-quality data" essentially dependent on the analytical methodology applied for characterization, this is integral to success. For routine products like tablets, capsules, and solutions, the regulatory guidelines, product-specific monographs, and pharmacopoeial annexures are set and "standard of operation." However, for nano-micro pharmaceuticals, regulatory guidelines are still evolving.
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1. Particle size analysis
2. Zeta potential and surface characterization (eg, porosity, BET, hydrophilicity, etc.)
3. Microscopic analysis (AFM, SEM, TEM) etc.
4. XRD-EDS- crystallinity, compatibility
5. Isotonicity, osmolarity, osmolality, plasma/blood compatibility
6. In vitro release testing (including Franz diffusion cells)
7. Nanoparticle tracking analysis
8. Chemical analysis
9. Thermal analysis- DSC, TGA etc.
10. Chromatographic analyses (all)
11. Drug loading, entrapment assays of nano and micro particles: current practices
12. Nanoparticle dissolution
13. Sterility testing nanoparticles
14. Lyophilization characterization
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A detailed examination of characterization techniques for micro- and nanoparticles in biomedicine
Covers the entire landscape of in vitro analytical techniques applied for characterization and analysis of micro-and nanoparticles in biomedicine
Examines limitations and challenges of currently used methodologies
Discusses new advances in the field of micro-nano characterization
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Produktdetaljer
ISBN
9780323961387
Publisert
2099-12-01
Utgiver
Elsevier Science Publishing Co Inc
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
480