Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers the most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear.

1. Introduction ; 2. DNA structure and stability: mutations versus repair ; 3. Regulation of gene expression ; 4. Growth factor signaling and oncogenes ; 5. The cell cycle ; 6. Growth inhibition and tumor suppressor genes ; 7. Apoptosis ; 8. Stem cells and consequences of blocked differentiation ; 9. Metastasis ; 10. Angiogenesis ; 11. Nutrients, hormones, and gene interactions ; 12. Tumour immunology and immunotherapy ; 13. Infectious agents and inflammation ; 14. New technologies and drug development

Dr Pecorino's monumental achievement highlights the most up-to-date and exciting discoveries ongoing in the molecular studies of cancer. * Professor David Lyden, Weill Cornell Medical College, Cornell University *Review from previous edition Review of previous edition: Pecorino gets the balance right between cell and molecular biology, focusing on mechanism rather than disease. Importantly the students like the text and can afford to buy the book. Therefore it is a real support to our learning program and actually used by the students. * Dr Bernard Mahon, Biology Department/Institute of Immunology, National University of Ireland, Ireland *Review of previous edition: The textbook is clearly written and the author does a great job of introducing some of the more fundamental concepts. The book is organized well and the topics flow smoothly and logically. The book also nicely pulls in current therapeutic approaches with the molecular lesions that are responsible for the generation of cancer. * Professor Deborah Vestal, Department of Biological Sciences, University of Toledo, USA *Review of previous edition: I found this book very helpful in understanding this otherwise very difficult subject. I think this is the only book which has been written for the learners. The writing style, illustrations and the unique features like 'pause and think' are unprecedented and very helpful. Lauren Pecorino must be a very good teacher. * Dr Waqqar Ali, Registrar Radiation Oncology, Cork University Hospital *Review of previous edition: Dr. Pecorino has done a fantastic job... The book's engaging writing-style and well thought out structure welcomes anyone with an interest in studying cancer in thorough, interesting detail. Reading this text was a pleasure, benefited me greatly educationally and made me feel like being a real part of the teaching - as though things were being explained to me in a one-on-one tutorial, an experience that most other medical textbooks don't provide! * Amazon.co.uk reviewer *