_
Personalized Immunosuppression in Transplantation: Role of Biomarker
Monitoring and Therapeutic Drug Monitoring _provides coverage of the
various approaches to monitoring immunosuppressants in transplant
patients, including the most recently developed biomarker monitoring
methods, pharmacogenomics approaches, and traditional therapeutic drug
monitoring.
The book is written for pathologists, toxicologists, and transplant
surgeons who are involved in the management of transplant patients,
offering them in-depth coverage of the management of immunosuppressant
therapy in transplant patients with the goal of maximum benefit from
drug therapy and minimal risk of drug toxicity.
This book also provides practical guidelines for managing
immunosuppressant therapy, including the therapeutic ranges of various
immunosuppressants, the pitfalls of methodologies used for
determination of these immunosuppressants in whole blood or plasma,
appropriate pharmacogenomics testing for organ transplant recipients,
and when biomarker monitoring could be helpful.
* Focuses on the personalized management of immunosuppression therapy
in individual transplant patients
* Presents information that applies to many areas, including gmass
spectrometry, assay design, assay validation, clinical chemistry, and
clinical pathology
* Provides practical guidelines for the initial selection and
subsequent modifications of immunosuppression therapy in individual
transplant patients
* Reviews the latest research in biomarker monitoring in
personalizing immunosuppressant therapy, including potential new
markers not currently used, but with great potential for future use
* Explains how monitoring graft-derived, circulating, cell free DNA
has shown promise in the early detection of transplant injury in
liquid biopsy
Les mer
Produktdetaljer
ISBN
9780128008850
Publisert
2015
Utgiver
Vendor
Elsevier (S&T)
Språk
Product language
Engelsk
Format
Product format
Digital bok
Forfatter