A practical, readable text which will give trainees, residents and practising hematologists up-to-date knowledge of the pathogenesis, clinical and laboratory features and management of blood disorders.

Contributors. Preface to the fifth edition. Preface to the first edition. 1 Stem Cells and Haemopoiesis. 2 Erythropoiesis. 3 Iron deficiency/ metabolism. 4 Iron overload. 5 Megaloblastic Anaemia. 6 Haemoglobin Defects. 7 Sickle Cell Anaemia. 8 Red Cell Membrane Disorders. 9 Red Cell Metabollic Disorders. 10 PNH. 11 Acquired HA. 12 Acquired Aplastic Anaemia. 13 Inherited Aplastic Anaemia. 14 Immunohaematology: Introduction. 15 Antigens in Human Blood. 16 Clinical Blood Transfusion. 17 Phagocytic white blood cells and their role in the host defence system. 18 Haemopoietic Growth Factors. 19 Storage Disorders. 20 Lymphocytes. 21 Immune Deficiency. 22 HIV. 23 Tissue Typing. 24 Stem Cell Transplantation. 25 Non-Myelopablative Transplantation. 26 Gene Therapy for Haematological Disorders. 27 Molecular Basis of Leukaemia and Lymphoma. 28 Classification of Acute Leukaemia. 29 Cytogenetics of Acute Leukaemia. 30 Clinical and Treatment Aspects of AML. 31 Adult AML. 32 Childhood AML. 33 Minimal Residual Disease in Acute Leukaemia. 34 Multi-Drug Resistance in Leukaemia. 35 Supportive Care in the Management of Acute Leukaemia. 36 Chronic Myeloid Leukaemia. 37 Chronic Lymphocytic Leukaemia. 38 T-Cell Lymphoproliferative Diseases. 39 Myelodysplastic Syndrome. 40 Myeloma. 41 Amyloidosis. 42Classification of Lymphomas. 43 Management of Hodgkin's Disease. 44 Management of Non-Hodgkin's Lymphoma. 45 Myeloproliferative Disorders. 46 Normal Haemostasis. 47 Platelets. 48 Congenital Bleeding- X linked disorders and Von Willebrand Disease. 49 (Rare Bleeding Disorders) Congenital Bleeding- autosomal recessive disorders. 50 Acquired Bleeding Disorders. 51 Thrombotic Thrombocytopenic Purpura (congenital and acquired) and Haemolytic Uraemic Syndrome. 52 Thrombosis- Congenital. 53 Venous Thrombosis- Acquired. 54 Management of Venous Thrombotic Disorders. 55 Congenital Platelet Disorders. 56 Acquired Immune Platelet Disorders. 57 Athero-thrombosis, Thrombolysis & Antiplatelets. 58 Haematological Aspects of Systemic Diseases. 59 Haematological Aspects of Tropical Diseases. 60 Neonatal Haematology. 61 Laboratory Practice. . Appendix 1: Normal Values. Appendix 2: WHO Classification of tumours of haemopoietic and lymphoid tissues. Index. .

"Completely revised to reflect the latest research in the field, this edition continues to provide trainees with up-to-date knowledge on the pathogenesis, clinical and laboratory features, and management of blood disorders. It covers the significant advances which have occurred in the application of cytogenetics and molecular genetics in the diagnosis, classification and understanding of haematological disorders ." (TMCnet.com, 8 December 2010)Quotes from review in the New England Journal of Medicine "Hoffbrand, Catovsky, and Tuddenham have managed to bring together a new edition (the fifth) of Postgraduate Haemotology in every chapter of which the reader finds very good, updated discussions..." "The editors have asked outstanding experts in every field to write new chapters or update previously included chapters." "Most hematologists need a revised and practical textbook in which they can rapidly search on the morning of a consultation...This book will be an important resource in such situations." Quotes from review in the European Journal of Haematology "...revised and transformed to appear today as the fifth edition of a modern and fully updated source of information for haematologist in training and consultants." "The book reflects the many and challenging professional aspects of being a specia-list in blood disorders. Reading the book as part of the postgraduate education and using the book as a readily accessible source of information will definitely contri-bute to confirm doctors in training and consultants why it is right to choose and practice haematology." Other Quotes "...this text undoubtedly provides an essential reference fro final-year Bsc, Msc and postgraduate research students specialising in haematology. All 1073 pages of it!" British Journal of Biomedical Science ‘Most haematologists need a revised and practical textbook in which they can rapidly search on the morning of a consultation… This book will be an important resource in such situations.' -- New England Journal of Medicine ‘…revised and transformed to appear today as the fifth edition of a modern and fully updated source of information for haematologist in training and consultants.' -- European Journal of Haematology