The Receptors, Volume III deals with receptors for interferons,
hormones, and growth factors as well as for ?-aminobutyric acid,
tuftsin, somatomedin, and insulin. Prolactin and nicotine receptors
are also considered, along with the protein tyrosine kinase activity
of hormone and growth factor receptors. Comprised of 12 chapters, this
volume begins with a detailed account of secretory component (SC) as a
receptor for polymeric immunoglobulins and the importance of
SC-polymeric immunoglobulin A interactions in the mucosal immune
system. The discussion then turns to interferon receptors and what is
known about the fate of interferons and their receptors after binding;
the use of muscimol in ligand-binding studies aimed at characterizing
?-aminobutyric acid receptors; and the role of protease nexins in the
interaction of proteases with cells and in the regulation of
proteolytic activity in the interstitial fluid immediately surrounding
cells. Subsequent chapters focus on receptor regulation of
phosphoinositides and calcium; effects of phospholipid turnover on
receptor function; dynamics of tuftsin receptors; and the structure,
function, and regulation of somatomedin receptors. The book also
examines the internalization and intracellular processing of insulin
receptors before concluding with an analysis of prolactin and nicotine
receptors. This monograph will be a valuable resource for students and
practitioners in fields ranging from cell biology and biochemistry to
physiology, endocrinology, and pharmacology.
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Produktdetaljer
ISBN
9781483273136
Publisert
2016
Utgiver
Vendor
Academic Press
Språk
Product language
Engelsk
Format
Product format
Digital bok
Forfatter