World-systems analysis has developed rapidly over the past thirty years. Today's students and junior scholars come to world-systems analysis as a well-established approach spanning all of the social sciences. The best world-systems scholarship, however, is spread across multiple methodologies and more than half a dozen academic disciplines. Aiming to crystallize forty years of progress and lay the groundwork for the continued development of the field, the Handbook of World-Systems Analysis is a comprehensive review of the state of the field of world-systems analysis since its origins almost forty years ago. The Handbook includes contributions from a global, interdisciplinary group of more than eighty world-systems scholars. The authors include founders of the field, mid-career scholars, and newly emerging voices. Each one presents a snapshot of an area of world-systems analysis as it exists today and presents a vision for the future. The clear style and broad scope of the Handbook will make it essential reading for students and scholars of anthropology, archaeology, geography, political science, history, sociology, and development economics.