Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others.
This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields.
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1. Advances and opportunity in design of microbial cell factories for production of biomolecules
2. Advances in long DNA synthesis
3. Discovery of enzymes responsible for cyclization and post-modification in triterpenoid biosynthesis
4. Synthetic biology for metabolic engineering of secondary metabolites
5. Synthetic biology design tools for metabolic engineering
6. Metabolic engineering for microbial cell factories
7. CRISPR based tools for microbial cell factories
8. Escherichia coli, the workhorse cell factory for the production of chemicals
9. Bacillus subtilis based microbial cell factories
10. Pseudomonas putida- based cell factories
11. Streptomyces based cell factories for production of biomolecules and bioactive metabolites
12. Corynebacterium glutamicum as a robust microbial factory for production of value-added proteins and small molecules: Fundamentals and applications
13. Production of high value-added chemicals in engineering methylotrophic cell factories
14. Cyanobacteria based microbial cell factories for production of industrial products
15. Integrated omics perspective to understand the production of high-value added biomolecules (HVABs) in microalgal cell factories
16. Saccharomyces cerevisiae as a microbial cell factory
17. Pichia pastoris based microbial cell factories
18. Yarrowia lipolytica engineering as a source of microbial cell factories
19. Engineering of microbial cell factories for production of plant-based natural products
20. Engineering of microbial cell factories for Omic-guided production of medically important biomolecules
21. Advances and applications of cell-free systems for metabolic production
22. Microbial biosensors for discovery and engineering of enzymes and metabolism
23. Manipulation of global regulators in Escherichia coli for the synthesis of biotechnologically relevant products
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Covers state-of-the-art tools and technologies used in the design and construction of microbial cell factories using biomolecules from renewable resources
Offers basic understanding and a clear picture of various MCFs
Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others
Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications
Highlights the advances, challenges, and future opportunities in designing MCFs
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Produktdetaljer
ISBN
9780128214770
Publisert
2021-02-18
Utgiver
Elsevier Science Publishing Co Inc
Vekt
1340 gr
Høyde
276 mm
Bredde
216 mm
Aldersnivå
P, UP, UU, 06, 05
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
488
Redaktør