This manual presents a systematic approach to procurement and examination of bone marrow by haematologists and oncologists. It is designed for medical students, house officers, physicians and other health professionals with an interest in haematology and oncology. It can also be used as a readily available, contemporary reference source for technologists and nurses who are involved in assisting in bone marrow aspiration, biopsy procurement and processing of marrow for cytological, immunological and histological examination. Although most practicing haematologists are familiar with bone marrow sampling techniques for diagnostic evaluation, there is a growing body of information that merits review, critical analysis and consolidation in one working reference, which this manual provides.