Human Drug Metabolism, An Introduction, Second Edition provides an
accessible introduction to the subject and will be particularly
invaluable to those who already have some understanding of the life
sciences. Completely revised and updated throughout, the new edition
focuses only on essential chemical detail and includes patient case
histories to illustrate the clinical consequences of changes in drug
metabolism and its impact on patient welfare. After underlining the
relationship between efficacy, toxicity and drug concentration, the
book then considers how metabolizing systems operate and how they
impact upon drug concentration, both under drug pressure and during
inhibition. Factors affecting drug metabolism, such as genetic
polymorphisms, age and diet are discussed and how metabolism can lead
to toxicity is explained. The book concludes with the role of drug
metabolism in the commercial development of therapeutic agents as well
as the pharmacology of some illicit drugs.
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An Introduction
Produktdetaljer
ISBN
9780470689349
Publisert
2018
Utgave
1. utgave
Utgiver
Vendor
Wiley-Blackwell
Språk
Product language
Engelsk
Format
Product format
Digital bok
Forfatter