Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail.
The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials.
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PART A Synthesis and characterization of PLGA nanoparticles for drug delivery
1. History, introduction, and properties of PLGA nanoparticles as drug delivery carriers
2. Preparation and characterization of PLGA nanoparticles
3. Drug loading methods and mechanism of drug release from PLGA nanoparticles
4. Biofate and cellular interactions of PLGA nanoparticles
PART B Application of PLGA nanoparticles in drug delivery
5. Targeting strategies using PLGA nanoparticles for efficient drug delivery
6. Current progress in PLGA-based nanoparticles for treatment of cancer diseases
7. PLGA-based nanoparticles for enhanced diagnosis and cancer therapy
8. PLGA-based nanoparticles for the treatment of inflammatory diseases
9. PLGA-based nanoparticles for treatment of cerebral diseases
10. PLGA-based nanoparticles for treatment of cardiovascular diseases
11. PLGA-based nanoparticles for treatment of infectious diseases
12. PLGA-based nanoparticles as regenerative medicine
13. Photodynamic and photothermal therapy using PLGA nanoparticles
14. Gene therapy using PLGA nanoparticles
PART C Recent advances and regulatory aspects in PLGA nanoparticles
15. Hybrid PLGA nanoparticles as advanced drug delivery and theranostic applications
16. Clinical translation of PLGA nanoparticles into the market
17. Biological toxicity and environmental hazards associated with PLGA nanoparticles
18. PLGA nanoparticles: Current uses and emerging trends
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A thorough resource that brings together preparation methods and novel applications of PLGA nanoparticles for drug delivery
Presents the fundamentals of PLGA nanoparticles, including properties, preparation, characterization, and biofate and cellular interactions
Provides in-depth coverage of a broad range of specific applications of PLGA nanoparticles across disease treatment, regenerative medicine and therapeutic areas
Offers a methodical approach to PLGA nanoparticles in drug delivery that is supported by data tables, illustrative figures and flowcharts
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Produktdetaljer
ISBN
9780323912150
Publisert
2022-03-02
Utgiver
Vendor
Elsevier - Health Sciences Division
Vekt
1110 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
532