This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research.

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This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers.

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Kuru: Introduction to Prion Diseases.- Anthropological Methods used in Kuru Research.- Nonhuman Primates in Research on Transmissible Spongiform Encephalopathies.- Clinical Features and Diagnosis of Human Prion Diseases.- Neuropathology, Immunohistochemistry, and Biochemistry in Human Prion Diseases.- Sub-Cellular and Molecular Changes Associated with Abnormal PrP Accumulation in Brain and Viscera of Classical and Atypical Prion Diseases.- Electron Microscopy of Prion Diseases.- Cell Death and Autophagy in Prion Diseases.- Methods for Isolation of Spiroplasma

 sp. from Prion Positive Eye Tissues of Sheep Affected with Terminal Scrapie.- Detection and Diagnosis of Prion Diseases using RT-QuIC: An  Update.- Analysis of Charge Isoforms of the Scrapie Prion Protein using Two-Dimensional Electrophoresis.- Exosomes in Prion Diseases.- Synthetic Mammalian Prions.- Biomarkers in Cerebrospinal Fluid.- The Use of Transgenic and Knock Out Mice in Prion Research.- Transgenic Mouse Models of Prion Diseases.

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This volume provides comprehensive information and detailed laboratory protocols used in the study of prion diseases. The chapters in this book cover topics such as: electron microscopy, neuropathology, immunohistochemistry, and immune-gold electron microscopy of prion diseases. Chapters also provide readers with detailed information about kuru, the clinical description of prion diseases, and the detection of prion protein and biomarkers. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and authoritative, Prion Diseases is a valuable resource for researchers and scientists in the exciting and rapidly growing field of prion disease research.

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Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts Includes supplementary material: sn.pub/extras
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GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
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Produktdetaljer

ISBN
9781493984176
Publisert
2018-08-14
Utgiver
Vendor
Humana Press Inc.
Høyde
254 mm
Bredde
178 mm
Aldersnivå
Professional/practitioner, P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet

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