Volume 2 of the APA Handbook of Pediatric Psychology, Developmental-Behavioral Pediatrics, and Developmental Science focuses on clinical applications of developmental science in pediatric psychology and developmental-behavioral pediatrics, discussing family systems and ecological contexts, child developmental contexts and child health conditions, and developmental-behavioral and mental health conditions.  The 29 chapters in this volume seek to build interdisciplinary bridges across a range of topics, including, but not limited to: Family processes and child outcomes in children with chronic health conditions Pediatric treatment adherence Pediatric medical traumatic stress Gender identity, gender dysphoria, and gender affirming models in childhood and adolescence Genetic disorders in childhood Pediatric obesity and implications for child health and well-being Autism spectrum disorder and disorders of social cognition across childhood and adolescence Preterm birth and implications for the family system and child and adolescent health and well-being Youth suicidal thinking and behavior prevention, intervention, and implications for child and adolescent health Developmental assessment of infants and toddlers Psychological consultation in inpatient pediatric medical settings Relationship-focused interventions and psychotherapy. This volume is written for researchers, practitioners, scholars, and trainees, as well as advanced students in these disciplines.