<p>“Molecular Imaging of Small Animals: Instrumentation and Applications, Zaidi … examines the most important techniques used for small-animal molecular imaging, analysing every aspect of each modality. … this publication should be available in all departments of nuclear medicine and diagnostic imaging, considering that molecular imaging is already living in the present.” (Giuseppe Danilo Di Stasio and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)</p>

This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development.

In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology andpathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

Read more
Molecular Imaging of Small Animals

Scintillation detectors for small-animal imaging.- Solid-state detectors for small-animal imaging.- Photodetectors for small-animal imaging instrumentation.- Design considerations of small-animal SPECT cameras.- Design considerations of small-animal PET scanners.- Design considerations of small-animal CT systems.- Small-animal MRI instrumentation.- Preclinical optical molecular imaging.- Advances in radiotracer development for molecular imaging.- Image registration for multimodality small-animal imaging.- Dual-modality preclinical SPECT/PET instrumentation.- Dual-modality preclinical SPECT/CT instrumentation.- Dual-modality preclinical PET/CT instrumentation.- Dual-modality preclinical SPECT/MR instrumentation.- Dual-modality preclinical PET/MR instrumentation.- Dual-modality preclinical PET/OI instrumentation.- Quantification of small-animal multimodality imaging data.- Animal handling and preparation for imaging.- Applications of molecular small-animal imaging in neurologyand psychiatry.- Applications of molecular small-animal imaging in cardiology.- Applications of molecular small-animal imaging in oncology.- Applications of molecular small-animal imaging in inflammation and infection.- Role of small-animal molecular imaging of gene expression.- Applications of molecular small-animal imaging in drug development.- Multimodality molecular imaging: A futuristic outlook.

Read more

This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development.

In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology andpathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

 

Read more
Explores the rapidly expanding field of multimodality small-animal molecular imaging Examines various imaging modalities including CT, MRI, SPECT and PET Demonstrates the increasing role of in vivo small-animal imaging in understanding human molecular biology and pathophysiology Includes supplementary material: sn.pub/extras
Read more
GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
Read more

Product details

ISBN
9781493908936
Published
2014-05-28
Publisher
Springer-Verlag New York Inc.
Height
235 mm
Width
155 mm
Age
Research, P, 06
Language
Product language
Engelsk
Format
Product format
Innbundet

Edited by

Biographical note

Habib Zaidi, Ph.D is Chief Physicist and head of the PET Instrumentation & Neuroimaging Laboratory at Geneva University Hospital and faculty member at the medical school of Geneva University. He is also a Professor of Medical Physics at the University Medical Center of Groningen (The Netherlands) and visiting Professor at Ecole Nationale Supérieure d’Electronique et de ses Applications (ENSEA, France). Dr. Zaidi is actively involved in developing imaging solutions for cutting-edge interdisciplinary biomedical research and clinical diagnosis in addition to lecturing undergraduate and postgraduate courses on medical physics and medical imaging.