International Review of Research in Developmental Disabilities, Volume 64 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Designing Interventions Targeting Social Isolation and Loneliness in Teens/Adults with IDD: Lessons Learned from Feasibility Studies, Designing syndrome-informed anticipatory interventions with community-based participatory principles, Babble Boot Camp in Down syndrome, Reevaluating Independence and Community for Persons with Intellectual Disabilities, What is Down syndrome? The perspective of adults with Down syndrome, and more. Additional chapters cover Newly discovered causes of severe and profound Intellectual Disability: Developmental and behavioral outcomes associated with Tubulinopathy and The Impact of Cognitive Engagement on Alpha and Beta Wave Patterns in the Motor Cortex: Exploring Associations for Children with Intellectual and Developmental Disabilities.