This textbook is a unique resource that demonstrates how engineering principles can be applied to solve medical challenges. It offers a toolkit on how to model heat, mass transfer, and fluid dynamics in the human body. The book discusses numerical solutions for physiological processes related to cryosurgery, hyperthermia, thermoregulation of the human body, thermal and fluid dynamics in coronary stents, magneto-hydrodynamics in the cardiovascular and respiratory systems, and cardiac acoustics. The book looks at physiological mechanisms that can be classified as Newtonian and Non-Newtonian fluids and clarifies how to leverage the Navier-Stokes equations, the first and second laws of thermodynamics, Fick's law, and Non-Newtonian principles to model them. This book is aimed at students and researchers interested in pursuing engineering studies with a focus on solving medical questions. Drawing from the editor’s 50 years of experience and knowledge gained in medical engineering, this book provides a practical and comprehensive approach to study thermo-haemo-dynamics in the human body. It explains how to model the described physiological process through worked examples and providing the equations behind the models.