This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on  MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization).  This is an ideal book for graduate students and researchers in the field of bioanalytical sciences.

This book also:

• Showcases new techniques and applications in MALDI MS
• Demonstrates how MALDI is preferable to ESI
• Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics