Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way of life. Its chemistry plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in the essential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry, but also for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods.
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Phosphorus plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. This volume is intended for the specialist in organophosphorus chemistry, and also as an introduction for the organic chemist with little experience in the field.
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1. Introduction to "Organophosphorus Chemistry" ; 2. The synthesis and applications of Phosphines ; 3. Applications of phosphorus (III) and (V) compounds as reagents in synthesis ; 4. The Wittig and related Reactions ; 5. Applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds ; 6. Preparation and reactions of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction ; 7. Phospho-Transfer processes leading to (P-C) bond formation ; 8. Low-coordinated phosphorus compounds ; 9. Phosphorus methods in nucleotide chemistry
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Written by an international group of experts in the field. It provides a survey of the literature, emphasising the most useful techniques and reagents.
Each chapter contains step-by-step protocols, essential background information and key citations in the literature.
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Dr Patrick J Murphy is currently a senior lecturer in Organic Chemistry at the University of Wales, Bangor. His research interests include organo-phosphorus chemistry, guanidine chemistry and natural product synthesis
Les mer
Written by an international group of experts in the field. It provides a survey of the literature, emphasising the most useful techniques and reagents.
Each chapter contains step-by-step protocols, essential background information and key citations in the literature.
Les mer
Produktdetaljer
ISBN
9780198502623
Publisert
2004
Utgiver
Oxford University Press
Vekt
568 gr
Høyde
242 mm
Bredde
162 mm
Dybde
20 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
288
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