Preface xvii About the Author xxxiii   Chapter 1: Mole Balances 1 1.1 The Rate of Reaction, –rA 4 1.2 The General Mole Balance Equation 8 1.3 Batch Reactors (BRs) 10 1.4 Continuous-Flow Reactors 12 1.5 Industrial Reactors 22   Chapter 2: Conversion and Reactor Sizing 31 2.1 Definition of Conversion 32 2.2 Batch Reactor Design Equations 32 2.3 Design Equations for Flow Reactors 35 2.4 Sizing Continuous-Flow Reactors 38 2.5 Reactors in Series 47 2.6 Some Further Definitions 58   Chapter 3: Rate Laws 69 3.1 Basic Definitions 70 3.2 The Reaction Order and the Rate Law 72 3.3 Rates and the Reaction Rate Constant 83 3.4 Present Status of Our Approach to Reactor Sizing and Design 93   Chapter 4: Stoichiometry 105 4.1 Batch Systems 107 4.2 Flow Systems 113 4.3 Reversible Reactions and Equilibrium Conversion 126   Chapter 5: Isothermal Reactor Design: Conversion 139 5.1 Design Structure for Isothermal Reactors 140 5.2 Batch Reactors (BRs) 144 5.3 Continuous-Stirred Tank Reactors (CSTRs) 152 5.4 Tubular Reactors 162 5.5 Pressure Drop in Reactors 169 5.6 Synthesizing the Design of a Chemical Plant 190   Chapter 6: Isothermal Reactor Design: Moles and Molar Flow Rates 207 6.1 The Molar Flow Rate Balance Algorithm 208 6.2 Mole Balances on CSTRs, PFRs, PBRs, and Batch Reactors 208 6.3 Application of the PFR Molar Flow Rate Algorithm to a Microreactor 212 6.4 Membrane Reactors 217 6.5 Unsteady-State Operation of Stirred Reactors 225 6.6 Semibatch Reactors 227   Chapter 7: Collection and Analysis of Rate Data 243 7.1 The Algorithm for Data Analysis 244 7.2 Determining the Reaction Order for Each of Two Reactants Using the Method of Excess 246 7.3 Integral Method 247 7.4 Differential Method of Analysis 251 7.5 Nonlinear Regression 258 7.6 Reaction-Rate Data from Differential Reactors 264 7.7 Experimental Planning 271   Chapter 8: Multiple Reactions 279 8.1 Definitions 280 8.2 Algorithm for Multiple Reactions 282 8.3 Parallel Reactions 285 8.4 Reactions in Series 294 8.5 Complex Reactions 304 8.6 Membrane Reactors to Improve Selectivity in Multiple Reactions 312 8.7 Sorting It All Out 317 8.8 The Fun Part 317   Chapter 9: Reaction Mechanisms, Pathways, Bioreactions, and Bioreactors 333 9.1 Active Intermediates and Nonelementary Rate Laws 334 9.2 Enzymatic Reaction Fundamentals 343 9.3 Inhibition of Enzyme Reactions 356 9.4 Bioreactors and Biosynthesis 364   Chapter 10: Catalysis and Catalytic Reactors 399 10.1 Catalysts 399 10.2 Steps in a Catalytic Reaction 405 10.3 Synthesizing a Rate Law, Mechanism, and Rate-Limiting Step 421 10.4 Heterogeneous Data Analysis for Reactor Design 436 10.5 Reaction Engineering in Microelectronic Fabrication 446 10.6 Model Discrimination 451 10.7 Catalyst Deactivation 454   Chapter 11: Nonisothermal Reactor Design—The Steady-State Energy Balance and Adiabatic PFR Applications 493 11.1 Rationale 494 11.2 The Energy Balance 495 11.3 The User-Friendly Energy Balance Equations 502 11.4 Adiabatic Operation 508 11.5 Adiabatic Equilibrium Conversion 518 11.6 Reactor Staging 522 11.7 Optimum Feed Temperature 526   Chapter 12: Steady-State Nonisothermal Reactor Design—Flow Reactors with Heat Exchange 539 12.1 Steady-State Tubular Reactor with Heat Exchange 540 12.2 Balance on the Heat-Transfer Fluid 543 12.3 Algorithm for PFR/PBR Design with Heat Effects 545 12.4 CSTR with Heat Effects 564 12.5 Multiple Steady States (MSS) 574 12.6 Nonisothermal Multiple Chemical Reactions 581 12.7 Radial and Axial Variations in a Tubular Reactor 595 12.8 Safety 603   Chapter 13: Unsteady-State Nonisothermal Reactor Design 629 13.1 Unsteady-State Energy Balance 630 13.2 Energy Balance on Batch Reactors 632 13.3 Semibatch Reactors with a Heat Exchanger 646 13.4 Unsteady Operation of a CSTR 651 13.5 Nonisothermal Multiple Reactions 656   Chapter 14: Mass Transfer Limitations in Reacting Systems 679 14.1 Diffusion Fundamentals 680 14.2 Binary Diffusion 684 14.3 Diffusion Through a Stagnant Film 688 14.4 The Mass Transfer Coefficient 690 14.5 What If . . . ? (Parameter Sensitivity) 705   Chapter 15: Diffusion and Reaction 719 15.1 Diffusion and Reactions in Homogeneous Systems 720 15.2 Diffusion and Reactions in Spherical Catalyst Pellets 720 15.3 The Internal Effectiveness Factor 730 15.4 Falsified Kinetics 737 15.5 Overall Effectiveness Factor 739 15.6 Estimation of Diffusion- and Reaction-Limited Regimes 743 15.7 Mass Transfer and Reaction in a Packed Bed 744 15.8 Determination of Limiting Situations from Reaction-Rate Data 750 15.9 Multiphase Reactors in the Professional Reference Shelf 751 15.10 Fluidized Bed Reactors 753 15.11 Chemical Vapor Deposition (CVD) 753   Chapter 16: Residence Time Distributions of Chemical Reactors 767 16.1 General Considerations 767 16.2 Measurement of the RTD 770 16.3 Characteristics of the RTD 777 16.4 RTD in Ideal Reactors 784 16.5 PFR/CSTR Series RTD 789 16.6 Diagnostics and Troubleshooting 793   Chapter 17: Predicting Conversion Directly from the Residence Time Distribution 807 17.1 Modeling Nonideal Reactors Using the RTD 808 17.2 Zero-Adjustable-Parameter Models 810 17.3 Using Software Packages 827 17.4 RTD and Multiple Reactions 830   Chapter 18: Models for Nonideal Reactors 845 18.1 Some Guidelines for Developing Models 846 18.2 The Tanks-in-Series (T-I-S) One-Parameter Model 848 18.3 Dispersion One-Parameter Model 852 18.4 Flow, Reaction, and Dispersion 854 18.5 Tanks-in-Series Model versus Dispersion Model 869 18.6 Numerical Solutions to Flows with Dispersion and Reaction 870 18.7 Two-Parameter Models—Modeling Real Reactors with Combinations of Ideal Reactors 871 18.8 Use of Software Packages to Determine the Model Parameters 880 18.9 Other Models of Nonideal Reactors Using CSTRs and PFRs 882 18.10 Applications to Pharmacokinetic Modeling 883   Appendix A: Numerical Techniques 897 A.1 Useful Integrals in Reactor Design 897 A.2 Equal-Area Graphical Differentiation 898 A.3 Solutions to Differential Equations 900 A.4 Numerical Evaluation of Integrals 901 A.5 Semilog Graphs 903 A.6 Software Packages 903   Appendix B: Ideal Gas Constant and Conversion Factors 905   Appendix C: Thermodynamic Relationships Involving the Equilibrium Constant 909   Appendix D: Software Packages 915 D.1 Polymath 915 D.2 MATLAB 916 D.3 Aspen 916 D.4 COMSOL Multiphysics 917   Appendix E: Rate Law Data 919   Appendix F: Nomenclature 921   Appendix G: Open-Ended Problems 925 G.1 Design of Reaction Engineering Experiment 925 G.2 Effective Lubricant Design 925 G.3 Peach Bottom Nuclear Reactor 925 G.4 Underground Wet Oxidation 926 G.5 Hydrodesulfurization Reactor Design 926 G.6 Continuous Bioprocessing 926 G.7 Methanol Synthesis 926 G.8 Cajun Seafood Gumbo 926 G.9 Alcohol Metabolism 927 G.10 Methanol Poisoning 928   Appendix H: Use of Computational Chemistry Software Packages 929   Appendix I: How to Use the CRE Web Resources 931 I.1 CRE Web Resources Components 931 I.2 How the Web Can Help Your Learning Style 933 I.3 Navigation 934   Index 937

Successfully integrates text, visuals, and computer simulations to help both undergraduate and graduate students master the fundamentals of chemical reaction engineering Contains new examples, problems, and video instruction helping students to explore key issues, seek optimum solutions, and practice critical thinking and creative problem-solving Presents expanded coverage of crucial safety topics to address the latest ABET requirements Includes expanded coverage of bioreactions and industrial chemistry, introduced with real reactors and reactions

In Elements of Chemical Reaction Engineering, Fifth Edition, H. Scott Fogler has updated Chapters 1-13 of Essentials of Chemical Reaction Engineering, added and will combine updated Chapters 11-14 of the Elements of Chemical Reaction Engineering. Fogler has added new examples and new problems to each chapter, and increased the emphasis on safety, fully reflecting the latest ABET requirements.        The result is a 17-chapter book targeting US graduate level courses, programs that wish to use Elements in the first undergraduate course and graduate course, and the international market (which overwhelming prefers to use Elements with its combination of undergrad and graduate materials).        Fogler is also recording video instruction to supplement this edition. In addition, eBook versions of this text will be available for the first time.