_Aptamers Engineered Nanocarriers for Cancer Therapy_ details the
selection technologies, biological characteristics, and clinical uses
of aptamer-based nano agents for cancer therapeutics. The book helps
facilitate speedy solutions for some of the problems pertaining to the
manufacture of nano-aptamers – such as toxicity, thermal stability,
cost efficiency, tumor penetration and blood stability. Key chapters
cover cell-SELEX technology for aptamer selection, mechanisms of
multi-drug resistance of cancer, the relevance of aptamers as
anticancer therapies, as well as the broad range of
aptamer-functionalized nanostructures available.
This book provides exciting insights into this relatively new approach
to cancer therapeutics, and will be of interest to materials
scientists, biomedical engineers, molecular biologists, biochemists
and clinical scientists, with a focus on cancer therapy.
* Reviews the mechanisms behind multi-drug resistance (MDR) in
cancer and how aptamer-mediated novel therapeutic agents and
strategies can facilitate MDR reversal
* Covers a range of aptamers engineered nanostructures, including
PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid
aptamers, and more
* Discusses the challenges associated with using aptamers as cancer
therapeutics and how this translates into clinical use
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Produktdetaljer
ISBN
9780323855761
Publisert
2022
Utgave
1. utgave
Utgiver
Elsevier S & T
Språk
Product language
Engelsk
Format
Product format
Digital bok
Forfatter