The text will help readers in establishing a strong foundation in the core principles and fundamental concepts of fluid mechanics. It further offers a unique opportunity to expand one's understanding of the dynamic relationship between fluid mechanics and cutting-edge technology. • Discusses fluid-structure interaction (FSI) in Industry 4.0, biofluid mechanics in medical applications, and fluid-induced vibration. • Illustrates fluid mechanics in microgravity and space applications, big data, and analytics in fluid mechanics. • Showcases how fluid mechanics plays a crucial role in diverse applications, such as space travel, medical advancements, and environmental solutions. • Explores how digital technologies like the Internet of Things (IoT), artificial intelligence (AI), and data analytics merge with fluid dynamics. • Offers problem-solving tools and strategies showcasing how fluid mechanics can address challenges ranging from noise reduction in machinery to efficient energy usage. The text is primarily written for senior undergraduates, and graduate students in diverse fields including mechanical engineering, industrial engineering, manufacturing engineering, chemical engineering, aerospace engineering, structural engineering, civil engineering, and automotive engineering.