This book constitutes the proceedings of the Second International Conference on HCI for Cybersecurity, Privacy and Trust, HCI-CPT 2020, held as part of the 22nd International Conference, HCI International 2020, which took place in Copenhagen, Denmark, in July 2020. The total of 1439 papers and 238 posters included in the 37 HCII 2020 proceedings volumes was carefully reviewed and selected from 6326 submissions. HCI-CPT 2020 includes a total of 45 regular papers; they were organized in topical sections named: human factors in cybersecurity; privacy and trust; usable security approaches.  As a result of the Danish Government's announcement, dated April21, 2020, to ban all large events (above 500 participants) until September 1, 2020, the HCII 2020 conference was held virtually.