This edited book features chapters from the 13th Pan-Hellenic and International Conference “ICT in Education,” Kavala, Greece, 2022. It examines how Information and Communication Technologies (ICT) are transforming education, focusing on technical, pedagogical, organizational, instructional, and policy aspects. A key emphasis is on applied research and how ICT tools enhance teaching and learning outcomes. The book highlights trends in e-learning and digital education, including curriculum design, learning environments, and teacher development. It also addresses instructional design, media selection, and engaging learning experiences. What distinguishes this volume is its focus on recent advancements, including insights from EU-funded international research. The chapters reflect the state of the art in educational technology, offering practical applications and the latest developments. This book is ideal for educators, policymakers, and researchers in pedagogy, informatics, educational technology, and teacher education.