Produktdetaljer
Biografisk notat
Kenneth Murphy is the Eugene Opie First Centennial Professor of Pathology and Immunology at Washington University School of Medicine in St. Louis. He received his MD/PhD degree from The Johns Hopkins University School of Medicine. He is a member of the National Academy of Sciences. Casey Weaver is the Wyatt and Susan Haskell Professor of Medical Excellence in the Department of Pathology at the University of Alabama at Birmingham School of Medicine. He received his MD degree from the University of Florida. His residency and post-doctoral training were completed at Barnes Hospital and Washington University in St. Louis.<em>"Now in a fully updated and expanded ninth edition "Janeway's Immunobiology" continues to be the premier textbook for students studying immunology at the undergraduate, graduate, and medical school levels. As an introductory text, students will appreciate the clear writing and informative illustrations, while advanced students and working immunologists will value its comprehensive scope and depth. This new edition of "Janeway's Immunobiology" presents immunology from a consistent point of view throughout -- that of the host's interaction with an environment full of microbes and pathogens. Now thoroughly revised ninth edition brings the content up-to-date with significant developments in the field, especially on the topic of innate immunity, and improving the presentation of topics across chapters for better continuity."</em> <br /><strong>James A. Cox, Library Bookwatch, February 2018</strong>
Part I: An Introduction to Immunobiology and Innate Immunity
Chapter 1: Basic Concepts in Immunology
Chapter 2: Innate Immunity: The First Lines of Defense
Chapter 3: The Induced Responses of Innate Immunity
Part II: The Recognition of Antigen
Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
Chapter 5: The Generation of Lymphocyte Antigen Receptors
Chapter 6: Antigen Presentation to T Lymphocytes
Part III: The Development of Mature Lymphocyte Receptor Repertoires
Chapter 7: Lymphocyte Receptor Signaling
Chapter 8: The Development and of B and T Lymphocytes
Part IV: The Adaptive Immune Response
Chapter 9: T Cell-Mediated Immunity
Chapter 10: The Humoral Immune Response
Chapter 11: Integrated Dynamics of Innate and Adaptive Immunity
Chapter 12: The Mucosal Immune System
Part V: The Immune System in Health and Disease
Chapter 13: Failures of Host Defense Mechanisms
Chapter 14: Allergy and Allergic Diseases
Chapter 15: Autoimmunity and Transplantation
Chapter 16: Manipulation of the Immune Response
This text presents the immune system from the point of view of the host’s interaction with an environment full of microbes and pathogens. New for the Ninth Edition, the text is now organised around the concept of modular immune responses, combining innate and adaptive immunity into effector modules and explaining the integration of the innate and adaptive immune response.
UPDATED TO REFLECT THE LATEST RESEARCH ADVANCES
The pace of discovery in immunology moves fast. New or expanded coverage includes: the latest developments on innate lymphoid cells and innate sensing mechanisms, including cyclic GMP-AMP synthase (cGAS) and activation of the STING pathway, an in-depth handling of follicular helper T cells and their role in B-cell class switching and affinity maturation, cytoskeletal reorganisation and integrin activation in antigen receptor signaling, expanded coverage on Akt and mTOR signaling and more.
A DYNAMIC ART PROGRAMME HELPS STUDENTS VISUALISE IMPORTANT CONCEPTS
Students benefit from distinct and consistent iconography designed to enhance and extend the principles presented in the text. The full-colour art programme also features micrographs and photographs that have been thoroughly updated to include better images of protein structure and more precise micrographs, plus 100 new figures have been added.
TOOLS TO ASSESS UNDERSTANDING
End-of-chapter questions have been completely revised and include a variety of question types to help students review important concepts. Additionally, the test bank, written by Leslie Berg (University of Massachusetts Medical School), features a comprehensive set of questions to assess student understanding.