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Bradykinin From Vasodilation to Neuroinflammation

Couture, Réjean
Heftet / 2025 / Engelsk

Produktdetaljer

ISBN
9780443289071
Publisert
2025-07-23
Utgiver
Elsevier Science Publishing Co Inc
Vekt
1090 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, UP, 06, 05
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
528

Redaktør
Couture, Réjean

Biografisk notat

Réjean Couture is currently Full Professor at the Department of Pharmacology and Physiology at the Faculty of Medicine, Université de Montréal in Canada. After completing a PhD in Pharmacology at University of Sherbrooke, Canada, he was awarded Fellowship Awards from the Medical Research Council of Canada (MRC) and the Fonds de la recherche en santé du Quebec (FRSQ) to pursue postdoctoral trainings in Pharmacology at Oxford University and in Neuroscience at McGill University. He is the author of over 225 original articles, books and book chapters, including 90 directly on kinins. He has supervised close to 60 graduate and postdoctoral students, many of whom now hold significant academic and other positions throughout Canada and internationally. He is known internationally for his seminal contributions in the field of Bradykinin and Substance P in pain and inflammation and in central autonomic control of blood pressure.

Bradykinin From Vasodilation to Neuroinflammation

Couture, Réjean
Heftet / 2025 / Engelsk
Couture, Réjean
Heftet / 2025 / Engelsk
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Bradykinin: From Vasodilation to Neuroinflammation, the latest release in the Molecular Mediators in Health and Disease series is a comprehensive guide to the multi-functional peptide bradykinin and its impact across the human body. The early chapters provide an overview of the biosynthesis and metabolism of bradykinin, understanding its receptors and signaling pathways, and the therapeutic value of agonists and antagonists for targeting these. This book explores the role of bradykinin in vascular, renal, and brain function, as well as its influence on various conditions and diseases, including inflammation, pain, cardiovascular disease, renal disease, obesity, ischemic stroke, and infectious diseases, including Covid-19. In addition to its foundational knowledge, the book includes extensive coverage of bradykinin biochemistry and molecular biology. It highlights the therapeutic potential of bradykinin, making it an ideal reference for researchers working in these fields. The book serves as an invaluable resource for understanding the complex roles of bradykinin and its applications in medical research and treatment.
Les mer
1. Introduction to bradykinin Réjean Couture 2. Tracing the historical journey: milestones and highlights of bradykinin Réjean Couture, Rahmeh Othman, Sébastien Talbot and Jean-Pierre Girolami 3. Kinin receptors and their signaling and regulation Fredrik Leeb-Lundberg 4. Animal models for studying bradykinin receptors Leonardo Martin, João Bosco Pesquero and Michael Bader 5. Peptide and nonpeptide ligands acting at bradykinin receptors François Marceau, Xavier Charest-Morin and Lajos Gera 6. Bradykinin-related peptides and their receptors from nonmammalian vertebrates Haixin Qin and Hang Fai Kwok 7. Bradykinin forming pathways and the pathogenesis of hereditary angioedema Allen P. Kaplan 8. Bradykinin in ACEI and other drug-induced angioedema Nancy J Brown 9. The kinins, a family of bioactive peptides that modulate inflammation Carlos D. Figueroa 10. Bradykinin in pain Robson da Costa, Marianne N. Manjavachi, Nara L.M. Quintão and Giselle F. Passos 11. Bradykinin in cardiovascular physiology and disease François Alhenc-Gelas, Nadine Bouby and Christine Richer-Giudicelli 12. Tissue kallikrein in therapeutic angiogenesis: from basic science to clinical applications Paolo Roberto Madeddu 13. Bradykinin in diabetes and obesity Alexandre Budu and Ronaldo Carvalho Araujo 14. Bradykinin in ocular health and diseases Menakshi Bhat, Réjean Couture and Elvire Vaucher 15. Kinin agonists as a means to increase blood–brain barrier permeability of drugs Juliette Latulippe, David Fortin and Fernand Gobeil 16. Bradykinin’s role in Alzheimer’s: protection or damage? Mariana Toricelli and Hudson Sousa Buck 17. Bradykinin receptors in neglected parasitic and viral diseases Julio Scharfstein 18. Bradykinin in cancer Gabriela Weirich Neculqueo and Maria Martha Campos
Les mer
Covers the biological role and impact of bradykinin across human health and illness
Explores the communication role of bradykinin in both homeostasis and pathologic states Investigates bradykinin across various conditions, including cardiovascular and renal disease, heart failure, diabetes, and cancer Discusses bradykinin receptors and their signaling pathways
Les mer

Relaterte produkter

Bradykinin: From Vasodilation to Neuroinflammation, the latest release in the Molecular Mediators in Health and Disease series is a comprehensive guide to the multi-functional peptide bradykinin and its impact across the human body. The early chapters provide an overview of the biosynthesis and metabolism of bradykinin, understanding its receptors and signaling pathways, and the therapeutic value of agonists and antagonists for targeting these. This book explores the role of bradykinin in vascular, renal, and brain function, as well as its influence on various conditions and diseases, including inflammation, pain, cardiovascular disease, renal disease, obesity, ischemic stroke, and infectious diseases, including Covid-19. In addition to its foundational knowledge, the book includes extensive coverage of bradykinin biochemistry and molecular biology. It highlights the therapeutic potential of bradykinin, making it an ideal reference for researchers working in these fields. The book serves as an invaluable resource for understanding the complex roles of bradykinin and its applications in medical research and treatment.
Les mer
1. Introduction to bradykinin Réjean Couture 2. Tracing the historical journey: milestones and highlights of bradykinin Réjean Couture, Rahmeh Othman, Sébastien Talbot and Jean-Pierre Girolami 3. Kinin receptors and their signaling and regulation Fredrik Leeb-Lundberg 4. Animal models for studying bradykinin receptors Leonardo Martin, João Bosco Pesquero and Michael Bader 5. Peptide and nonpeptide ligands acting at bradykinin receptors François Marceau, Xavier Charest-Morin and Lajos Gera 6. Bradykinin-related peptides and their receptors from nonmammalian vertebrates Haixin Qin and Hang Fai Kwok 7. Bradykinin forming pathways and the pathogenesis of hereditary angioedema Allen P. Kaplan 8. Bradykinin in ACEI and other drug-induced angioedema Nancy J Brown 9. The kinins, a family of bioactive peptides that modulate inflammation Carlos D. Figueroa 10. Bradykinin in pain Robson da Costa, Marianne N. Manjavachi, Nara L.M. Quintão and Giselle F. Passos 11. Bradykinin in cardiovascular physiology and disease François Alhenc-Gelas, Nadine Bouby and Christine Richer-Giudicelli 12. Tissue kallikrein in therapeutic angiogenesis: from basic science to clinical applications Paolo Roberto Madeddu 13. Bradykinin in diabetes and obesity Alexandre Budu and Ronaldo Carvalho Araujo 14. Bradykinin in ocular health and diseases Menakshi Bhat, Réjean Couture and Elvire Vaucher 15. Kinin agonists as a means to increase blood–brain barrier permeability of drugs Juliette Latulippe, David Fortin and Fernand Gobeil 16. Bradykinin’s role in Alzheimer’s: protection or damage? Mariana Toricelli and Hudson Sousa Buck 17. Bradykinin receptors in neglected parasitic and viral diseases Julio Scharfstein 18. Bradykinin in cancer Gabriela Weirich Neculqueo and Maria Martha Campos
Les mer
Covers the biological role and impact of bradykinin across human health and illness
Explores the communication role of bradykinin in both homeostasis and pathologic states Investigates bradykinin across various conditions, including cardiovascular and renal disease, heart failure, diabetes, and cancer Discusses bradykinin receptors and their signaling pathways
Les mer

Produktdetaljer

ISBN
9780443289071
Publisert
2025-07-23
Utgiver
Elsevier Science Publishing Co Inc
Vekt
1090 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, UP, 06, 05
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
528

Redaktør
Couture, Réjean

Biografisk notat

Réjean Couture is currently Full Professor at the Department of Pharmacology and Physiology at the Faculty of Medicine, Université de Montréal in Canada. After completing a PhD in Pharmacology at University of Sherbrooke, Canada, he was awarded Fellowship Awards from the Medical Research Council of Canada (MRC) and the Fonds de la recherche en santé du Quebec (FRSQ) to pursue postdoctoral trainings in Pharmacology at Oxford University and in Neuroscience at McGill University. He is the author of over 225 original articles, books and book chapters, including 90 directly on kinins. He has supervised close to 60 graduate and postdoctoral students, many of whom now hold significant academic and other positions throughout Canada and internationally. He is known internationally for his seminal contributions in the field of Bradykinin and Substance P in pain and inflammation and in central autonomic control of blood pressure.

Relaterte produkter