Immunity to Immunotherapy in Cancer: Mechanisms and Limitations explores the intricate interplay between cancer therapy and the immune system, addressing why some patients do not respond to immunotherapy and scientific solutions in development. The book examines molecular strategies of immune evasion within the tumor microenvironment, providing insights into factors like tumor heterogeneity and immune checkpoint mechanisms that contribute to resistance. Highlighting promising approaches such as combination therapies, personalized medicine, and novel immunotherapeutic agents, the book aims to enhance patient outcomes and advance cancer immunotherapy. Designed as a comprehensive guide for professionals and researchers, this textbook offers an overview of the latest scientific discoveries and practical applications in cancer therapy. It serves as an invaluable resource for scientists, doctors, academicians, and students, presenting a path toward more effective, non-toxic, and customized cancer treatments. This book is essential for anyone interested in the future of cancer therapy.
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Part A: Cancer Immunity 1. Introduction to Immunity in Cancer 2. Role of Innate Immunity in Cancer Immunology 3. Role of Dendritic Cells in Cancer Immunology 4. Role of Natural Killer Cells in Cancer Immunology 5. Role of B-Cells in Tumor Immunity 6. Role of CD4+ T-Cells in Cancer Immunology 7. Role of Regulatory T-Cells and Th17 Cells in Tumor Microenvironment 8. Role of Monocytes, Macrophages, and Polymorphonuclear Cells in Cancer Immunology 9. Role of Cytokines in Cancer Immunology 10. Role of Chemokines and Chemokine Receptors in Cancer Immunology 11. Role of the Inflammasome in Cancer Immunology 12. Current Advanced Immunological Tools and Databases in Tumor Immunity 13. Tumor Heterogeneity and Therapeutic Resistance Part B: Cancer Immunotherapy 14. Cancer Immunotherapy: Pros, Cons, and Beyond 15. Role of Monoclonal Antibody, Immune Checkpoint Inhibitors, and Programmed Death Ligand 1 in Cancer Immunotherapy 16. Role of Chimeric Antigen Receptor-T Cell in Cancer Immunotherapy 17. Role of Small Molecule-Based Drugs in Cancer Immunotherapy 18. Role of Adoptive Cell Therapy in Cancer Immunotherapy 19. Role of Cancer Vaccines in Cancer Immunotherapy 20. Role of Radiotherapy/Chemotherapy in Cancer Immunotherapy
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Presents an innovative exploration of the complex interaction between cancer therapy and the immune system
Provides an in-depth examination of the molecular strategies of immune evasion and the tumor microenvironment, offering critical insights into why some patients do not respond to immunotherapy Bridges the gap between current research and practical therapeutic applications in cancer immunotherapy Highlights the latest advancements in cancer therapy, discussing cutting-edge strategies such as combination therapies, personalized medicine, and novel immunotherapeutic agents
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Produktdetaljer

ISBN
9780443415517
Publisert
2026-06-01
Utgiver
Elsevier Science Publishing Co Inc
Vekt
450 gr
Høyde
235 mm
Bredde
191 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
570

Biografisk notat

Experienced Associate Professor in Pharmacology with a demonstrated history of working in national and international organisations. Strong professional skilled in Pharmaceutical Research, Molecular Biology, Inflammation, and cardiovascular and metabolic diseases. Dr. Deepa Mandlik is an Associate Professor at Bharati Vidyapeeth (Deemed to be University) Poona College of Pharmacy, Pune. She brings extensive teaching and research experience across her career and has demonstrated outstanding academic achievement in her early training. She has published extensively in reputable national and international journals and has authored several pharmaceutical books along with multiple international book chapters. A recognized PhD guide, she mentors doctoral researchers and oversees a active cohort of postgraduate students. She is a life member of APTI and a member of CRS-Indian Chapter. Her research interests encompass nanotechnology, targeted drug delivery, quality by design, design of experiments, and optimization techniques, reflecting a strong commitment to innovation in pharmaceutical science. Dr. Mandlik is known for integrating rigorous scientific inquiry with teaching and mentorship to advance the development of the next generation of pharmaceutical researchers.