Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological and physicochemical perspectives. The book is comprised of three main parts, with the first discussing the biochemical aspects of oxidative stress modulation. Other sections cover physiological and pathophysiological aspects on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer’s disease, liver transplant, and cancer. Final content is dedicated to pharmacological aspects and includes chapters on phytotherapy and flavonoids.
This book is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out.
Les mer
1. Antioxidants as modulators of the Ubiquitin-proteasome system against aging and proteinopathies
2. Modulation of oxidative stress by S-nitrosation and other thiol modifications
3. Regulation of Nrf2 Signaling Pathway and the Hallmarks of Aging: An Overview
4. Fluid redox biomarkers in neurological disease
5. CCM proteins are key players in redox signaling and oxidative stress regulation in Cerebral
6. Effects of maternal and early life nutrition on redox homeostasis
7. Mitochondria-associated membranes (MAMs) as modulators of oxidative stress in Alzheimer's disease
8. Oxidative stress biomarkers in human health and disease
9. Modulation of the antioxidant defense system against pathophysiological redox imbalance in cardiovascular diseases
10. Modulation of cancer cell proliferation by interfering with metabolic ROS production
11. Modulation of human hydrogen sulfide metabolism by physiological effectors
12. Intestinal redox and Inflammatory Bowel Disease
13. Applications of Plant-Derived Products in Photodynamic Therapy
14. Hopes and disappointments related to the use of flavonoids in therapeutical approaches
15. Omega-3 nutritional intervention as therapeutic coadjuvant approach to improve Rett Syndrome clinical and biochemical features
16. A glance on antioxidants: the role of sulfur amino acids in retinal disorders
17. Oxidative stress and antioxidant-based therapies in couple infertility
18. Modulation of oxidative stress in psoriasis: Pathophysiology and therapy
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“...offers a broad overview of recent developments in the search for new and more reliable means for the early diagnosis and reliable evaluation of oxidative stress-linked pathologies as well as recent studies evaluating potential nutritional and pharmacological preventives and treatments…. A helpful feature of the book is provision in the preface of quarter- to half-page long summaries of each of its eighteen chapters, a practice that other book editors would do well to imitate. Overall, each chapter is concisely and clearly written. The text is complemented by multiple figures and tables... [and] offers a wide-ranging survey of current research on the diagnosis, pathology, and treatment or prevention of deleterious effects due to oxidative stress…. The readability and balance of the book renders it suitable as a text. --©Doody’s Review Service, 2024, Peter J. Kennelly, PhD (Virginia Tech)
Les mer
Explores the modulation of oxidative stress using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological, and physicochemical perspectives
Provides the latest updates in the fast-developing field of REDOX biochemistry and pharmacology
Presents content that is clear and easy to read
Useful for researchers and instructors in many fields
Produktdetaljer
ISBN
9780443192470
Publisert
2023-08-07
Utgiver
Vendor
Academic Press Inc
Vekt
840 gr
Høyde
276 mm
Bredde
216 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
306