"I have found this to be a comprehensive, yet highly focused text on malignancies. Dr. Weber’s work covers nicely the interface of physiology and molecular mechanisms in the development and maintenance of malignant cells. The review of the founding pathologic observations is useful in providing a backdrop for today’s highly molecular approaches. A deep understanding of the molecular workings of malignant disease is critical to the development of not only therapeutics, but also diagnostics and I have found this text to be highly relevant as a resource to these ends". (Gary A. Pestano, PhD, Director, Discovery Life Sciences, Ventana Medical Systems, Inc., Tucson, Arizona USA)

"Whereas the field of cancer research has increased in complexity over the past decades, this book presents a comprehensive compendium of molecular mechanisms of malignancy and reflects the author's unique vision on pathophysiologic associations that may define general molecular requirements of invasive tumors. This book reaches beyond the current view and understanding of molecular mechanisms of malignancies and prompts the reader to reflect on the current knowledge from a different angle". (Professor Dr. med. H.-P. Bruch, Head of the Department of Surgery, Klinik fuer Chirurgie, Univeritatsklinikum, Schleswig-Holstein, Luebeck, Germany)

"I have found this to be a comprehensive, yet highly focused text on malignancies. Dr. Weber's work covers nicely the interface of physiology and molecular mechanisms in the development and maintenance of malignant cells. The review of the founding pathologic observations is useful in providing a backdrop for today's highly molecular approaches. A deep understanding of the molecular workings of malignant disease is critical to the development of not only therapeutics, but also diagnostics and I have found this text to be highly relevant as a resource to these ends". (Gary A. Pestano, PhD, Director, Discovery Life Sciences, Ventana Medical Systems, Inc., Tucson, Arizona USA) "Whereas the field of cancer research has increased in complexity over the past decades, this book presents a comprehensive compendium of molecular mechanisms of malignancy and reflects the author's unique vision on pathophysiologic associations that may define general molecular requirements of invasive tumors. This book reaches beyond the current view and understanding of molecular mechanisms of malignancies and prompts the reader to reflect on the current knowledge from a different angle". (Professor Dr. med. H.-P. Bruch, Head of the Department of Surgery, Klinik fuer Chirurgie, Univeritatsklinikum, Schleswig-Holstein, Luebeck, Germany)

Comprehensive text Highly systematic structure Explains mechanisms of molecular interactions Description of functions ranges from basic cellular mechanisms to specific clinical syndromes Covers common and rare tumors, sporadic and inherited cancers

GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com