LIFE: A Transdisciplinary Inquiry examines nature, cognition and society as an interwoven tapestry across disciplinary boundaries. This volume explores how information and communication are instrumental in and for living systems, acknowledging an integrative account of media as environments and technologies. The aim of the collection is a fuller and richer account of everyday life through a spectrum of insights from internationally known scholars of the natural sciences (physical and life sciences), social sciences and the arts. How or should life be defined? If life is a medium, how is it mediated? Viewed as interactions, transactions and contexts of ecosystems, life can be recognized through patterns across the sciences, including metabolisms, habitats and lifeworlds. The book also integrates discussions of embodiment, ecological values, literacies and critiques, with bioinspired, synthetic and historical design approaches to envision what could constitute artful living in an ever-evolving, interdependent world. The volume foregrounds systemic approaches to life, drawing on a wide range of disciplines and fields, including architecture, art, biology, bioengineering, chemistry, cinema studies, communication, computer science, conservation, cultural studies, design, ecology, environmental studies, information science, landscape architecture, geography, journalism, materials science, media archaeology, media studies, philosophy, physics, plant signalling and development, political economy, sociology and system dynamics. This is the second volume in the MEDIA • LIFE • UNIVERSE Trilogy. It follows and builds upon the 2021 collection MEDIA: A Transdisciplinary Inquiry ISBN 9781789382655