Then, network models of memory, rhythm generation and spatial navigation are presented, followed by abstract and biophysical models of synaptic plasticity.

This is the 2nd edition of a very well received and popular book that reflects the current state-of-the-art of the ongoing research avenues concerning the hippocampus and processing units bridging the gap between single cell activity, network activity and global brain function. It aims to provide a methodology to anyone interested in developing microcircuit level models of the hippocampus.

The book is divided into two thematic areas: (I) Experimental background and (II) Computational analysis. In part I, leading experimental neuroscientists discuss the morphological, physiological and molecular characteristics as well as the connectivity and synaptic properties of the various cell types found in the hippocampus. Behaviour-related ensemble activity patterns of morphologically identified neurons in anesthetized and freely moving animals provide insights on the function of the hippocampal areas. In part II, computational neuroscientists present models of the hippocampalmicrocircuits at various levels of detail (e.g. single cell level, network level, etc.). Synaptomics and connectomics models of hippocampal structures are initially discussed. Then, network models of memory, rhythm generation and spatial navigation are presented, followed by abstract and biophysical models of synaptic plasticity. Network models of hippocampal implicated disorders (epilepsy and schizophrenia) are then detailed and how their network topologies, connectivities and activities change in these diseases. Finally, two chapters are dedicated to describing simulator environments of single neurons and networks currently used by computational neuroscientists in developing their models and modelling tools to parametrically constrain them.     

This engaging volume is invaluable to experimental and computational neuroscientists, electrical engineers, physicists, mathematicians and others interested in developing microcircuit models of the hippocampus. Graduatelevel students and trainees in all of these fields can find this book a significant source of information.


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Presents snapshots of experimental evidence Targets exclusive audience interested in developing microcircuit models of the hippocampus Suggests a pedagogic methodology approach of modeling microcircuits Discusses the latest experimental and computational research Explores areas for future research
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GPSR Compliance The European Union's (EU) General Product Safety Regulation (GPSR) is a set of rules that requires consumer products to be safe and our obligations to ensure this. If you have any concerns about our products you can contact us on ProductSafety@springernature.com. In case Publisher is established outside the EU, the EU authorized representative is: Springer Nature Customer Service Center GmbH Europaplatz 3 69115 Heidelberg, Germany ProductSafety@springernature.com
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Produktdetaljer

ISBN
9783319991023
Publisert
2019-02-21
Utgave
2. utgave
Utgiver
Springer International Publishing AG
Høyde
235 mm
Bredde
155 mm
Aldersnivå
Professional/practitioner, UF, 08
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
17