"This is an excellent book covering molecular mechanisms underlying non-canonical autophagy and the therapeutic potential and development of autophagy modulators. There are very few books which cover the molecular mechanisms underlying non-canonical autophagy. Weighted Numerical Score: 85 - 3 Stars" --© Doody’s Review Service, 2021, Omer Iqbal, reviewer, expert opinion
Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies.
Les mer
1. Introduction: canonical vs non-canonical autophagy
2. Overview of Canonical Autophagy
3. Overview of Non-Canonical Autophagy
4. LC3-associated phagocytosis (LAP)
5. Autophagy-dependent cell death (ADCD)
6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls
Les mer
Offers a valuable, in-depth guide to the mechanistic and pathophysiological features of non-canonical autophagy
Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy
Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes
Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development
Les mer
Produktdetaljer
ISBN
9780128205389
Publisert
2021-04-26
Utgiver
Elsevier Science Publishing Co Inc
Vekt
290 gr
Høyde
229 mm
Bredde
152 mm
Aldersnivå
P, 06
Språk
Product language
Engelsk
Format
Product format
Heftet
Antall sider
182