This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed. New: expands on DNA nanotechnology and presents the fundamentals and new development of RNA therapeutics including CRISPR/Cas9, RNA editing and mRNA vaccines.
- Novel backbones for therapeutic nucleic acids.
- Lipid-, peptide- and protein-oligonucleotide conjugates.
- Modified DNA nanostructures.
- Aptamers and DNA catalysts.
- RNA therapeutics.
Les mer
Produktdetaljer
ISBN
9783111424682
Publisert
2025-09-01
Utgave
2. utgave
Utgiver
De Gruyter
Høyde
240 mm
Bredde
170 mm
Aldersnivå
P, UP, 06, 05
Språk
Product language
Engelsk
Format
Product format
Innbundet
Antall sider
438
Redaktør
Biografisk notat
Ramon Eritja, Institute for Advanced Chemistry of Catalonia, Barcelona, Spain.