1. Transporter proteins and its implication in human diseases Ritika Kabra and Shailza Singh 2. Protein kinase CK2 inhibition as a pharmacological strategy Christian Borgo and Maria Ruzzene 3. Emerging role of protein kinases in diabetes mellitus: From mechanism to therapy Preeti Gupta, Aaliya Taiyab, and Md Imtaiyaz Hassan 4. Dual roles of ATP-binding site in protein kinases: Orthosteric inhibition and allosteric regulation Mingyu Li, Ashfaq Ur Rehman, Yaqin Liu, Kai Chen, and Shaoyong Lu 5. Pseudokinases: Prospects for expanding the therapeutic targets armamentarium Nayana Devang, Adyashree Pani, and G.K. Rajanikant 6. Chemogenomics and bioinformatics approaches for prioritizing kinases as drug targets for neglected tropical diseases Joyce Villa Verde Bastos Borba, Arthur Carvalho Silva, Marilia Nunes Nascimento Lima, Sabrina Silva Mendonca, Nicholas Furnham, Fabio Trindade Maranhão Costa, and Carolina Horta Andrade 7. Targeting malaria protein kinases G.C. Cassiano, T.A. Tavella, M.N. Nascimento, D.A. Rodrigues, P.V.L. Cravo, Carolina Horta Andrade, and Fabio Trindade Maranhão Costa 8. Yeast-based high-throughput screens for discovery of kinase inhibitors for neglected diseases T.A. Tavella, G.C. Cassiano, Fabio Trindade Maranhão Costa, P. Sunnerhagen, and E. Bilsland 9. Structural studies of full-length receptor tyrosine kinases and their implications for drug design Adam Bajinting and Ho Leung Ng

Contains timely chapters written by well-renown authorities in their field Includes a number of high-quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students Integrates experimental and computational methods for studying the role of protein kinases in different diseases, along with sections on the design of suitable protein kinase inhibitors for use in the treatment of patients