This book offers an overview of salt stress, which has a devastating effect on the yields of various agricultural crops around the globe. Excessive salts in soil reduce the availability of water, inhibit metabolic processes, and affect nutrient composition, osmotic balance, and hydraulic conductivity. Plants have developed a number of tolerance mechanisms, such as various compatible solutes, polyamines, reactive oxygen species and antioxidant defense mechanisms, ion transport and compartmentalization of injurious ions. The exploitation of genetic variation, use of plant hormones, mineral nutrients, soil microbe interactions, and other mechanical practices are of prime importance in agriculture, and as such have been the subject of multidisciplinary research.