This book constitutes the refereed proceedings of the 12th International Symposium on Fundamentals of Computation Theory, FCT '99, held in Iasi, Romania in August/September 1999.The 42 revised full papers presented together with four invited papers were carefully selected from a total of 102 submissions. Among the topics addressed are abstract data types, algorithms and data structures, automata and formal languages, categorical and topological approaches, complexity, computational geometry, concurrency, cryptology, distributed computing, logics in computer science, process algebras, symbolic computation, molecular computing, quantum computing, etc.