_The 31st European Symposium on Computer Aided Process Engineering: ESCAPE-31, Volume 50_ contains the papers presented at the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Istanbul, Turkey. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students and consultants in the chemical industries. * Presents findings and discussions from the 31st European Symposium of Computer Aided Process Engineering (ESCAPE) event