Voet, Voet and Pratt's Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. While continuing in its tradition of presenting complete and balanced coverage that is clearly written and relevant to human health and disease, Fundamentals of Biochemistry, 5e includes new pedagogy and enhanced visuals that provide a pathway for student learning.
The authors are careful to present new information such that it links it to existing content, ever mindful that students assimilate new information only in the proper context. The enriched assessment content in WileyPLUS Learning Space offers students the opportunity to gauge their conceptual understanding and receive immediate feedback to address misconceptions.
Voet, Voet and Pratt's Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future.
Preface xv
Acknowledgments xix
Guide to Media Resource
PART I INTRODUCTION
1 Introduction to the Chemistry of Life 1
2 Water 23
PART II BIOMOLECULES
3 Nucleotides, Nucleic Acids, and Genetic Information 42
4 Amino Acids 80
5 Proteins: Primary Structure 97
6 Proteins: Three-Dimensional Structure 131
7 Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies 180
8 Carbohydrates 221
9 Lipids and Biological Membranes 245
10 Membrane Transport 293
PART III ENZYMES
11 Enzymatic Catalysis 322
12 Enzyme Kinetics, Inhibition, and Control 361
13 Biochemical Signaling 402
PART IV METABOLISM
14 Introduction to Metabolism 442
15 Glucose Catabolism 478
16 Glycogen Metabolism and Gluconeogenesis 523
17 Citric Acid Cycle 558
18 Electron Transport and Oxidative Phosphorylation 588
19 Photosynthesis: Can be found at www.wiley.com/college/voet and in WileyPLUS Learning Space
20 Lipid Metabolism 664
21 Amino Acid Metabolism 718
22 Mammalian Fuel Metabolism: Integration and Regulation 773
PART V GENE EXPRESSION AND REPLICATION
23 Nucleotide Metabolism 802
24 Nucleic Acid Structure 831
25 DNA Replication, Repair, and Recombination 879
26 Transcription and RNA Processing 938
27 Protein Synthesis 982
28 Regulation of Gene Expression 1033
Solutions: Can be found at www.wiley.com/college/voet and in WileyPLUS Learning Space Glossary G-1
Index I-1
Produktdetaljer
Biographical note
Donald Voet received a Ph.D. in chemistry from Harvard University and did postdoctoral research in the Biology Department at MIT. Don took up a faculty position in the department of chemistry at the University of Pennsylvania, upon completing his postdoctoral work. He has been a visiting scholar at Oxford University, the University of California San Diego, and the Weismann Institute of Science in Israel.
Judith Voet received her Ph.D. from Brandeis University and did postdoctoral research at the University of Pennsylvania, Haverford College and the Fox Chase Cancer Center. She taught at the University of Delaware before moving to Swarthmore College. Together with Don Voet, she is Co-Editor-in-Chief of the journal Biochemistry and Molecular Biology Education.