Minimal neoplasia may be defined as a small cancer that has progressed beyond its site of primary origin into the surrounding tissue, but that has not yet reached the stage of deeper invasion or metastasization.

General Aspects.- Minimal Neoplasia as a Challenge for Early Cancer Detection.- Morphology of Minimal Invasion.- Molecular Biology of Minimal Invasion.- Minimal Neoplasias in Experimental Liver Carcinogenesis.- Pathology and Therapy.- Minimal Endometrial Carcinoma.- Therapeutic Procedure for Minimal Endometrial Cancer.- Minimal Cervical Cancer: Definition and Histology.- Therapy of Minimal Cervical Cancer.- Anatomic Markers of Human Mammary Premalignancy and Incipient Breast Cancer.- Treatment Aspects of Minimal Breast Cancer.- Incipient Prostate Cancer: Definition, Histology, and Clinical Consequences.- Incipient Cancer of the Colon: Definition and Histology.- Immunological Approaches for Early Cancer Detection.- Therapeutic Consequences of Minimal Neoplasia of the Colon.- Early Cancer of the Lung.- Minimal Thyroid Neoplasia.- Minimal Thyroid Cancer: Clinical Consequences.- Cryptic Gliomas.- Cytogenetics of Preleukemic Stages in Experimental and Human Leukemogenesis.- Preleukemia: Bone Marrow Histopathology in Myelodysplasia and Preleukemic Syndrome.- Cytobiology and Clinical Findings of Myelodysplastic Syndromes.- Incipient Malignant Lymphoma: Definition and Histopathology.

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