The work is a 'one-stop' text for trainees and consultants in Endocrinology and Diabetes, residents, those preparing for sub-specialty exams and other professionals allied to the area who need to gain an understanding of the field. It acts as both a point of reference for the experienced consultant as well as a trusted training resource.

1. Principles of basic and clinical endocrinology 1.1: Lynn Loriaux: Endocrine Practice Fundamentals 1.2: John W. Funder: Hormones and receptors: fundamental considerations 1.3: Ken Siddle and Gemma Brierley: Molecular aspects of hormonal regulation 1.4: Janine A. Danks and Samantha J. Richardson: Endocrinology and evolution: lessons from comparative endocrinology 1.5: James Gibney, Indi Banerjee, and Ken Ho: Hormones Across the Lifespan 1.6: Brian Keevil, Peter Trainer, and William Drake: Pituitary assessment strategy 1.7: Simon Pearce and Catherine Owen: Endocrine autoimmunity 1.8: Jerome Bertherat, Anne Jouinot, and Fidéline Bonnet-Serrano: Common Features of Endocrine Tumours 1.9: Trevor Cole: Genetic Aspects of Endocrine Disease 1.10: George Mastorakos, Markella Nezi, Djuro Macut, and Maria Papagianni: Environmental Influences on Endocrine Disease 1.11: Georg Brabant and H. Oster: Endocrinology, sleep and circadian rhythms 1.12: Richard Ross: Principles of Hormone replacement 1.13: Jonathan Valabhji and Rochan Agha-Jaffar: Prevention in endocrinology 2. Pituitary and hypothalamic diseases 2.1: John Morris: Functional anatomy of the hypothalamus and pituitary 2.2: Stephen G. Ball: The neurohypophysis 2.3: Aetiology, pathogenesis, and management of disease of the pituitary 2.3.1: Mehul T. Dattani and Louise C. Gregory: Development of the pituitary and genetic forms of hypopituitarism 2.3.2: Shlomo Melmed: Molecular pathogenesis of pituitary tumours 2.3.3: Luis Syro, Kalman Kovacs, and Fabio Rotondo: Histopathology of pituitary tumours 2.3.4: Jean-Francois Bonneville, Sonia Nagi, and Iulia Potorac: Imaging of the pituitary 2.3.5: Miles J. Levy, Ragini Bhake, and Narendra Reddy: Hypopituitarism: replacement of adrenal, thyroid, and gonadal axes 2.3.6: Jens Jørgensen: Adult growth hormone deficiency 2.3.7: Edward R. Laws Jr, David L. Penn, and Caroline S. Repetti: Surgery of pituitary tumours 2.3.8: Naomi Fersht and Francesca Solda: Pituitary radiotherapy 2.3.9: Nicholas Tritos and Anne Klibanski: Prolactinomas and hyperprolactinaemia (including macroprolactinaemia) 2.3.10: John Wass, Peter J. Trainer, and Márta Korbonits: Acromegaly 2.3.11: Nienke Biermasz and Wouter R. van Furth: Clinically nonfunctioning pituitary tumours and gonadotropinomas 2.3.12: Mark Gurnell, Olympia Koulouri, and Waiel Bashari: Thyrotropinomas 2.3.13: Ann McCormack: Pituitary carcinoma 2.3.14: Niki Karavitaki, Shu Teng Chai, and Shahzada Ahmed: Pituitary incidentalomas 2.4: Aetiology, pathogenesis, and management of diseases of the hypothalamus 2.4.1: Mehul Dattani, Hoong-Wei Gan, and Manuela Cerbone: Hypothalamic dysfunction (hypothalamic syndromes) 2.4.2: Niki Karavitaki: Craniopharyngiomas 2.4.3: Jürgen Honegger, Ulrike Ernemann, and Rudi Beschorner: Perisellar tumours including cysts, hamartomas, and vascular tumours 2.4.4: Mark E. Molitch and Jelena Kravarusic: Lymphocytic hypophysitis and other inflammatory conditions of the pituitary 2.5: Susan M Webb, Anna Aulinas, Cristina Colom, and José Barahona: Pineal physiology and pathophysiology, including pineal tumours 3. The Thyroid 3.1: Evaluation of the thyroid patient 3.1.1: Robert Volpé and Clark Sawin: The history and iconography relating to the thyroid gland 3.1.2: W. Edward Visser: Biosynthesis, transport, metabolism, and actions of thyroid hormones 3.1.3: Inge Bülow Pedersen and Stig Andersen: Clinical assessment of the thyroid patient 3.1.4: Ulla Feldt-Rasmussen: Thyroid function tests and the effects of drugs 3.1.5: Robin P. Peeters and Anita Boelen: Nonthyroidal illness syndrome 3.1.6: Steen Bonnema and Laszlo Hegedüs: Thyroid imaging: nuclear medicine techniques 3.1.7: Laszlo Hegedüs and Finn N. Bennedbæk: Thyroid imaging: nonisotopic techniques 3.1.8: Mark P. J. Vanderpump: Epidemiology of thyroid disease and swelling 3.2: Aetiology of thyroid disorders 3.2.1: Terry Davies, Francesca Menconi, and Yaron Tomer: The complex genetics of thyroid disease 3.2.2: Josef Köhrle: Environmental factors 3.2.3: Michael B. Zimmermann: Iodine deficiency disorders 3.2.4: Shunichi Yamashita, Furio Pacini, and Rossella Elisei: Radiation-induced thyroid disease 3.2.5: Anthony P. Weetman: Autoimmune thyroid disease 3.2.6: Elizabeth N. Pearce and Alan Farwell: Thyroiditis 3.3: Thyrotoxicosis and related disorders 3.3.1: Claudio Marcocci and Filomena Cetani: Clinical assessment and systemic manifestations of thyrotoxicosis 3.3.2: Annie W. C. Kung and C.L. Cheung: Thyrotoxic periodic paralysis 3.3.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska: Thyrotoxic storm 3.3.4: Simon Pearce: Subclinical hyperthyroidism 3.3.5: Francesco Latrofa and Paolo Vitti: Causes and laboratory investigations of thyrotoxicosis 3.3.6: Luigi Bartalena: Anti-thyroid drug treatment for thyrotoxicosis 3.3.7: Markus Luster and Michael Lassmann: Radio-iodine treatment of hyperthyroidism 3.3.8: Nancy Dugal Perrier, Orlo Clark, and Sarah B. Fisher: Surgery for thyrotoxicosis 3.3.9: Jacques Orgiazzi: Management of Graves hyperthyroidism 3.3.10: Wilmar M. Wiersinga: Graves orbitopathy and dermopathy 3.3.11: Dagmar Führer and Holger Jäschke: Management of toxic multinodular goitre and toxic adenoma 3.3.12: Wilmar M. Wiersinga: Management of thyrotoxicosis without hyperthyroidism 3.4: Hypothyroidism 3.4.1: Massimo Tonacchera and Luca Chiovato: Clinical assessment and systemic manifestations of hypothyroidism 3.4.2: Ferruccio Santini: Causes and laboratory investigation of hypothyroidism 3.4.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska: Myxoedema coma 3.4.4: Bijay Vaidya and Chantal Daumerie: Subclinical hypothyroidism 3.4.5: Mark Gurnell, Carla Moran, and V. K. Chatterjee: Syndromes of Resistance to Thyroid Hormone 3.4.6: Birte Nygaard: Treatment of hypothyroidism 3.5: Thyroid lumps 3.5.1: Dagmar Führer and Holger Jäschke: Pathogenesis of nontoxic goitre 3.5.2: Hans Graf and Gilberto Paz Filho: Management of nontoxic multinodular goitre 3.5.3: Laszlo Hegedüs and Finn N. Bennedbæk: Management of the single thyroid nodule 3.5.4: Massimo Santoro, Barbara Jarzab, Jolanta Krajewska, and Dagmara Rusinek: Pathogenesis of thyroid cancer 3.5.5: Fulvio Basolo and Clara Ugolini: Pathology of thyroid cancer 3.5.6: Corin Badiu and Ruxandra Dobrescu: Papillary, follicular, and anaplastic thyroid carcinoma and lymphoma 3.5.7: Friedhelm Raue and Karin Frank-Raue: Medullary thyroid carcinoma 4. Parathyroid, calcium, and bone metabolism 4.1: David Goltzman and Geoffrey N. Hendy: Parathyroid anatomy, hormone synthesis, secretion, action, and receptors 4.2: Claudio Marcocci, Federica Saponaro, and Filomena Cetani: Hypercalcaemia 4.3: John P. Bilezikian: Primary hyperparathyroidism 4.4: Dolores Shoback and Muriel Babey: Familial Hypocalciuric Hypercalcemia Types 1-3 and Neonatal Severe Primary Hyperparathyroidism 4.5: Rajesh Thakker, Bart Clarke, and Fadil M. Hannan: Hypocalcaemic disorders, hypoparathyroidism, and pseudohypoparathyroidism 4.6: Paul D. Miller and Michael Pazianas: Bones and the KidneyDLThe Practical Conundrum: Distinguishing Between Osteoporosis and the Bone Diseases that Accompany Chronic Renal Failure 4.7: Laleh Ardeshirpour, Thomas O. Carpenter, and Cemre Robinson: Hypercalcaemic and hypocalcaemic syndromes in children 4.8: Richard Eastell: Osteoporosis 4.9: Graham R. Williams, J. H. Duncan Bassett, Bernard Freudenthal, and Laura M. Watts: Thyroid disorders and bone disease 4.10: Socrates E. Papapoulos: Paget s disease of bone 4.11: Michael P. Whyte: Rickets and osteomalacia (acquired and heritable forms) 4.12: Gherardo Mazziotti, Ernesto Canalis, and John P. Bilezikian: Glucocorticoid-induced osteoporosis 5. The adrenal gland and endocrine hypertension 5.1: Peter Guest: Adrenal imaging 5.2: Fausto Palazzo and Radu Mihai: Adrenal surgery 5.3: Irina Bancos, Massimo Terzolo, and Wiebke Arlt: Adrenal incidentaloma 5.4: Jérôme Bertherat, Rossella Libè, and Anne Jouinot: Adrenocortical cancer 5.5.1: Eamonn R. Maher and Ruth T Casey: Genetics of phaeochromocytomas, paragangliomas, and neuroblastoma 5.5.2: Henri Timmers: Management of phaeochromocytoma and paragagnlioma 5.6.1: Maria Christina Zennaro, Fabio Fernandes-Rosa, and Sheerazed Boulkroun: Genetics of primary aldosteronism and other steroid-related causes of endocrine hypertension 5.6.2: Morris Brown and Will Drake: Management of primary aldosteronism 5.7: John Newell-Price: Cushing s syndrome 5.8.1: Li Chan and Shwetha Ramachandrappa: Genetics of Adrenal Insufficiency 5.8.2: Wiebke Arlt: Management of Adrenal Insufficiency 5.9.1: Nils P. Krone: Genetics of congenital adrenal hyperplasia 5.9.2: Richard J. Auchus: Modern management of congenital adrenal hyperplasia and prospects for the future 6. Neuroendocrine tumours and genetic disorders 6.1: Guido Rindi and Rajaventhan Srirajaskanthan: Overview and Pathophysiology of Neuroendocrine Neoplasms 6.2: Whaljit Dhillo and Paul Bech: Neuroendocrine tumour markers 6.3: Rajaventhan Srirajaskanthan, Martyn E. Caplin, and Dominique Clement: Carcinoid syndrome  6.4.1: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Lung neuroendocrine tumours 6.4.2: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Non-functioning pancreatic neuroendocrine tumours 6.5: Christos Toumpanakis and Martyn E. Caplin: Gastrinoma 6.6: Ashley Grossman and Ingrid YF Mak: Insulinoma and hypoglycaemia 6.7: Karim Meeran: Glucagonoma 6.8: Alia Munir: Vasointestinal Polypeptide Secreting Tumours 6.9: John Wass: Somatostatinoma 6.10: Prakash Manoharan: Imaging neuroendocrine tumours of the gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours (GEP-NET) 6.11: Rajesh V. Thakker: Multiple endocrine neoplasia type 1 6.12: Electron Kebebew, Douglas Wiseman, and Mustapha El Lakis: Multiple endocrine neoplasia type 2a and 2b 6.13: Eamonn R. Maher and Ruth T. Casey: Familial syndromes and genetic causes of paraganglioma and phaeochromocytoma   6.14: Constantine A. Stratakis and Fabio Faucz: Carney s complex 6.15: Michael A. Levine and Steven A. Lietman: Molecular and Clinical Characteristics Of the McCune-Albright Syndrome 6.16: Charis Eng, Lamis Yehia, and Shreya Malhotra: Cowden syndrome 7. Growth and development during childhood and adolescence 7.1: Growth and its Disorders 7.1.1: Gary Butler: Recognising Normal and Disordered Growth 7.1.2: Alexander A. L. Jorge, Fernanda A. Correa, and Renata C. Scalco: Disorders of the GH-IGF Axis 7.1.3: Anita Hokken-Koelega: Short stature in children born small for gestational age 7.1.4: Steve Chernausek and Minu George: Growth Disorders with no defined aetiology 7.1.5: Lars Savendahl and Emelie Benji: Tall Stature 7.2: Sex Development 7.2.1: Olaf Hiort and Ralf Werner: Sex Determination and Differentiation 7.2.2: S. Faisal Ahmed and Salma R. Ali: Disorders of Sex Development (DSD) in the newborn 7.2.3: Alan Rogol and John Fuqua: Recognising Normal and Disordered Pubertal Development 7.2.4: Alan Rogol and John Fuqua: Pubertal Delay and Hypogonadism 7.2.5: Julianne Leger and Jean-Claude Carel: Precocious Puberty 7.3: Helena Gleeson and Rohana Wright: Transition In Endocrinology 8. Female endocrinology and pregnancy 8.1: Normal female endocrinology and ovarian disorders 8.1.1: Chris McCartney and John Marshall: Neuroendocrinology of reproduction: the role of hypothalamus and pituitary 8.1.2: Terhi Piltonen and Juha Tapanainen: Ovarian and uterine development from fetal life to puberty 8.1.3: Gurkan Bozdag, Baris Ata, and Engin Türkgeldi: Menstrual cycle and ovulation 8.2: Evaluation of the female patient with suspected reproductive endocrine disorders 8.2.1: Channa Jayasena, Steve Franks, and Rachel Roberts: Clinical evaluation of patient with suspected reproductive endocrine disorders 8.2.2: Daniel Dumesic and Zain Al-Safi: Laboratory evaluation 8.3: Reproductive endocrine disorders 8.3.1: Sarah L. Berga: Disorders of gonadotrophin secreton 8.3.2: Julian R. E. Davis and Agnieszka Swiecicka: Hyperprolactinaemia 8.3.3: Deepthi Lavu, Radha Indusekhar, and Shaughn O'Brien: Premenstrual syndrome 8.4: Polycystic ovary syndrome and other androgen excess disorders 8.4.1: Bulent Yildiz and Sezcan Mumusoglu: Polycystic ovary syndrome: definitions, phenotypes, prevalence and genetics 8.4.2: R Jeffrey Chang: Polycystic ovary syndrome: reproductive aspects 8.4.3: David Ehrmann and Susan Sam: Polycystic ovary syndrome: metabolic aspects 8.4.4: Duarte Pignatelli, Ricardo Azziz, and Bulent Yildiz: Polycystic ovary syndrome: Hirsutism 8.5: Female hypogonadism and menopause 8.5.1: Ephia Yasmin and Gerard S. Conway: Female hypogonadism: premature ovarian insufficiency 8.5.2: Dimitrios G. Goulis, Stavroula A. Paschou, and Panagiotis Anagnostis: Female hypogonadism: Endocrinology of the menopause and hormone replacement therapy 8.6: Female infertility 8.6.1: Adam Balen and Susie Jacob: Female Infertility and assisted reproduction 8.6.2: Kutluk Oktay and Enes Taylan: Female infertility: fertility preservation 8.7: Hormonal contraception 8.7.1: Jennifer Chin Bliss Kaneshiro: Hormonal contraception 8.8: Exogenous factors and female repoductive health 8.8.1: Alessandra Gambineri and Daniela Ibarra-Gasparini: Exogenous factors and female reproductive health: common extragonadal endocrinopathies affecting reproduction 8.8.2: Siew Lim, Aya Mousa, Soulmaz Shorakae, and Lisa Moran: Exogenous factors and female reproductive health: nutrition and reproduction 8.8.3: Evy Diamanti-Kandarakis and Eleni A Kandaraki: Exogenous factors and female reproductive health: envrionment and reproduction 9. Endocrinology of pregnancy 9.1: Endocrine disorders of Pregnancy 9.1.1: Peter Taylor, LDKE Premawardhana, and John Lazarus: General considerations relating to thyroid disease in pregnancy 9.1.2: Kris Poppe, Flora Veltri, and David Unuane: Management of thyroid disorders before assisted and spontaneous pregnancy 9.1.3: Tim Korevaar and Robin Peeters: Thyroid disease during pregnancy 9.1.4: Nobuyuki Amino and Naoko Arata: Management of thyroid disorders after pregnancy 9.1.5: A. S. Paul van Trotsenburg Nitash and Zwaveling-Soonawala: Thyroid disorders in newborns, infants and children 9.1.6: Mark Molitch and Wenyu Huang: Pituitary tumours in pregnancy 9.1.7: Paul Carroll, Niki Karavitaki, and Kirstie Lithgow: Other disorders of the pituitary and hypothalamus in pregnancy 9.1.8: David Torpy, Michael O'Reilly, and Sunita De Sousa: Adrenal disease in pregnancy 9.1.9: Jeremy Cox and Stephen Robinson: Endocrine bone disease in pregnancy 9.1.10: Sandra Lowe: Imaging of endocrine disorders in pregnancy 10. Male Reproductive Endocrinology 10.1: Normal male reproductive endocrinology 10.1.1: Ilpo Huhtaniemi and Jorma Toppari: Endocrine and local regulation of testicular hormone and sperm production 10.1.2: Dirk Vanderschueren, Leen Antonio, Nari Kim, and Frank Claessens: Sex steroid actions in the Male 10.2: Evaluation of the male patient with suspected hypogonadism and/or infertility 10.2.1: Bradley Anawalt: Clinical evaluation 10.2.2: Jean-Marc Kaufman: Endocrine evaluation 10.2.3: Jackson Kirkman-Brown and Sarah J Conner: Diagnostic Semen analysis 10.3: Male reproductive endocrine disorders 10.3.1: Claus H. Gravholt: Klinefelter s syndrome 10.3.2: Adult Hypogonadism: Aetiology 10.3.2.1: Alvin Matsumoto and Radhika Narla: Etiology of Hypogonadism 10.3.2.2: Giovanni Corona, Mario Maggi, and Giulia Rastrelli: Types of Treatments 10.3.2.3: Michael Zitzmann: Gonadotrophin induction of spermatogenesis 10.3.2.4: Shehzad Basaria and Thiago Gagliano-Juca: Male Hypogonadism: Benefits of Testosterone Treatment 10.3.2.5: Adrian Dobs and Swaytha Yalamanchi: Risks of T Treatment 10.3.3: Herman J. Tournaye and Biljana Popovic-Todorovic: Management of Idiopathic male infertility 10.3.4: Mathis Grossmann, B. Yeap, and Gary Wittert: Hypothalamo-pituitary-testicular axis fucntion in systemic diseases and effects of medications 10.3.5: Vincenzo Rochira, Antonio R. M. Granata, and Cesare Carani: Management of sexual dysfunction 10.3.6: Stephanie Page and Maritza Farrant: Hormonal male contraception 10.3.7: Glenn Braunstein: Gynaecomastia 10.4: Exogenous factors and male reproductive health 10.4.1: Jorma Toppari: Environmental influences on male reproductive health 10.4.2: David Handelsman: Androgen Misuse and Abuse 11. Management of the Transgender Patient 11.1: Jon Arcelus and Walter Bouman: Introduction to Transgender and Gender Diverse People 11.2: Daniel Klink: Endocrine Treatment of Transgender Youth 11.3: Vin Tangpricha and Craig Sineath: Hormone Therapy in transgender women 11.4: Guy T'Sjoen and Justine Defreyne: Hormone therapy in transgender men 11.5: Chloë De Roo and Guy T'Sjoen: Fertility Options for Transgender Persons  12. Endocrine Responses to Systemic Diseases or Substance Use 12.1: Endocrinology of systemic disease 12.1.1: David Henley, Thomas Upton, and Stafford L. Lightman: The endocrine response to stress 12.1.2: Greet Van den Berghe and Lies Langouche: Endocrinology in the critically ill 12.1.3: David Johnson, Melissa Nataatmadja, and Yeoungjee Cho: Hormones and the kidney 12.1.4: Jacob George and Mohammed Eslam: The endocrinology of liver disease 12.1.5: Steven K. Grinspoon and Takara Stanley: Endocrine abnormalities in HIV infection 12.1.6: Karen Miller: The endocrinology of anorexia nervosa 12.2: Endocrine Complications of Substance Misuse  12.2.1: Marc Walter and Margit Proescholdt: Endocrinology and alcohol 12.2.2: Peter Sonksen and Richard Holt: Use and abuse of performance-enhancing hormones in sport 12.2.3: Ashley Grossman, Eleni Armeni, and Bernard Khoo: Effect of Opioids on Adrenal and Reproductive Endocrinology 13. Endocrinology of cancer 13.1: Endocrine Disorders Caused by Cancer or its Treatment 13.1.1: Thomas Papathomas and Vania Nose: Metastatic Disease in Endocrine Organs 13.1.2: David W. Ray: Paraneoplastic endocrine syndromes 13.1.3: Claire Higham and Rob Murray: Long-term endocrine sequelae of cancer therapy 13.1.4: Carla Moran: Endocrine complications of biological cancer therapies 13.2: Hormonal therapy for breast and prostatic cancers 13.2.1: Rob Clarke and Alice Greenhalgh: The breast: lactation and breast cancer as an endocrine disease 13.2.2: Amna Sheri and Laura Morrison: Endocrine treatment of breast cancer 13.2.3: Irina A. Vasilevskaya, Matthew J. Schiewer, and Karen E. Knudsen: Hormonal Therapy for Prostate Cancer: Molecular basis of efficacy and therapeutic bypass 14. Obesity, lipids, and metabolic disorders 14.1: Obesity 14.1.1: Anthony Coll: The Physiology of Bodyweight Regulation 14.1.2: Adrian Bauman: Obesity as a Public Health Problem 14.1.3: Rachel Batterham and Friedrich Jassil: Medical Complications of Obesity  14.1.4: John Wilding and Jonathan Lim: Dietary and Medical Management of Obesity 14.1.5: Francesco Rubino, Vivian Anastasiou, Luca Ferraro, Dalal Qanaq, and Ghassan Chamseddine: Metabolic Surgery 14.1.6: Sadaf Farooqi: Assessment of Obesity in Children 14.1.7: Russell Viner and Billy White: Management of Obesity in Children and Young People 14.1.8: Nick Finer: Planning obesity care pathways 14.2: Lipoprotein metabolism and dyslipidaemia 14.2.1: Bo Angelin and Paolo Parini: Lipoprotein metabolism 14.2.2: Stefano Romeo, Bo Angelin, and Paolo Parini: Genetic forms of dyslipidaemia 14.3: Other metabolic disorders 14.3.1: Khalid Hussain and Sonya Galcheva: Hyperinsulinaemic Hypoglycaemia 14.3.2: Phillip Gorden and Noemi Malandrino: Autoimmune Hypoglycaemia  14.3.3: Robin H. Lachmann: Disorders of carbohydrate metabolism 14.3.4: Yves Deugnier and Edouard Bardou-Jacquet: Haemochromatosis And Other Inherited Diseases Of Iron Metabolism 14.3.5: Michael N. Badminton and Danja Schulenburg-Brand: The porphyrias 15. Diabetes mellitus 15.1: Introduction to Diabetes Mellitus 15.1.1: Shanta Persaud and Peter Jones: Physiology of glucose homeostasis 15.1.2: Stephen Colagiuri and Crystal Man Ying Lee: Classification and diagnosis of diabetes mellitus 15.2: Aetiopathogenesis and Diagnosis of Type 1 Diabetes 15.2.1: Elizabeth J. Mayer-Davis and Daria Igudesman: Epidemiology and Public Health 15.2.2: Augustin Brooks: Presentation and Natural History 15.2.3: Richard Oram, Susan Wong, and Ayat Bashir: Pathogenesis 15.3: Aetiopathogenesis and Diagnosis of Type 2 Diabetes 15.3.1: Sarah Wild and Jackie Price: Epidemiology and Public Health 15.3.2: Roy Taylor: Presentation and Natural History 15.3.3: Mark Walker, Xuefei Yu, and Amalia Gastaldelli: Pathogenesis 15.4: Non Type 1, Non Type 2 Diabetes 15.4.1: Katherine Owen: Diagnosis of non type 1, non type 2 forms of diabetes 15.5: Principles of Management of Diabetes 15.5.1: Simon Heller and Jackie Elliott: Structured Education 15.5.2: John Pickup and Nick Oliver: Glucose Monitoring and Sensing 15.5.3: Pratik Choudhary and Peter Jacob: Insulins and insulin delivery devices 15.5.4: Clifford Bailey and Melanie Davies: Non-insulin glucose lowering agents 15.5.5: Stephanie Amiel: Hypoglycaemia in the treatment of diabetes mellitus 15.6: Evidence-based Management of Type 1 Diabetes 15.6.1: Peter Hammond and Fiona Campbell: Strategies for management of type 1 diabetes 15.6.2: Christel Hendrieckx and Jane Speight: Psychological and Behavioural Aspects of Type 1 Diabetes Management 15.6.3: Colin Dayan and Danijela Tatovic: Immunotherapy for type 1 diabetes 15.6.4: Peter Senior, Martin Drage, Anneliese Flatt, and Chris Callaghan: Transplantation (islet and solid organ) 15.7: Evidence-based Prevention and Management of Type 2 Diabetes 15.7.1: Peter Winocour and Sagen Zac-Varghese: Strategies for management of type 2 diabetes 15.7.2: Jane Speight and Tim Skinner: Psychological and Behavioural Aspects of Type 2 Diabetes Management 15.7.3: Kamiesh Khunti and Nitin Narayan Gholap: Type 2 diabetes in different ethnic groups 15.7.4: Nicholas Wareham: Prevention of Type 2 Diabetes 15.8: Emerging Approaches to Restoring Euglycaemia in Diabetes 15.8.1: Michael White, Timothy J. Kieffer, and Cara Ellis: Regenerative medicine for diabetes 15.8.2: Roman Hovorka and Charlotte Boughton: Closed loop 15.9: Emergency and Hospital management of Diabetes 15.9.1: Ketan Dhatariya: Hyperglycaemic Emergencies 15.9.2: Gerry Rayman: Management of the inpatient with diabetes mellitus 15.9.3: Greet Van Den Berghe and Jan Gunst: Care of diabetes in ICU and peri-sugery 15.10: Specialised Management of Other forms of Diabetes 15.10.1: Andrew Hattersley, Kashyap Patel, and Rachel Besser: Monogenic forms of diabetes resulting from beta cell dysfunction 15.10.2: Anna Stears, David B. Savage, and Stephen O'Rahilly: Lipodystrophies and severe insulin resistance 15.10.3.1: Phil Weston: Diabetes Secondary to Pancreatic Disease 15.10.3.2: Jeremy Tomlinson: Diabetes Secondary to Endocrine Disorders 15.10.4: Helen Murphy and Jennifer M Yamamoto: Diabetes in Pregnancy 15.11: Psychiatry and Diabetes 15.11.1: Khalida Ismail, Christopher Garrett, and Marietta Stadler: Type 1 diabetes and Psychiatry 15.11.2: Khalida Ismail, Hermione Price, Marilia Calcia, Calum Moulton, and Clare Whicher: Type 2 diabetes and Psychiatry 15.12: Microvascular Complications of Diabetes 15.12.1: Angela Shore: Pathogenesis of Microvascular Complications 15.12.2: Peter Scanlon: Retinopathy 15.12.3: Luigi Gnudi and Sally Marshall: Diabetic Nephropathy 15.12.4: Solomon Tesfaye and Jing Wu: Diabetic Neuropathy 15.13: Macrovascular Disease in Diabetes 15.13.1: Mark Kearney, Peysh Patel, and Richard Cubbon: Mechanisms of macrovascular disease in diabetes 15.13.2: Naveed Sattar: Macrovascular disease in type 2 diabetes 15.13.3: John Petrie: Macrovascular disease in type 1 diabetes 15.13.4: Bruno Vergès: Diabetic dyslipidaemia 15.13.5: Bryan Williams: Hypertension in diabetes mellitus 15.14: The Diabetic Foot 15.14.1: Frank Bowling and Andrew Boulton: Modern management of diabetes-related foot disease 15.15: Delivery of Diabetes Care 15.15.1: Jonathan Valabhji: Diabetes service organisation 15.15.2: Philip Clarke and Tom Lung: Health Economics of Diabetes Care and Prevention

Fully comprehensive evidence-based and highly valued reference work Contains wide-ranging and pragmatic advice on diagnosis, with clear guidelines for recommended management, while also covering the underlying scientific principles 15 overarching sections, with new sections on Endocrinology of Pregnancy and Management of the Transgender Patient included Over 800 images complementing the extensive text and information provided Includes full access to the online edition of the textbook

Professor Wass is a Professor of Endocrinology at Oxford University and was the Head of the Department of Endocrinology at the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital Oxford, UK until 2011. From 1989 he was Professor of Clinical Endocrinology and Sub-Dean, University of London at Bart>'s. He founded and ran the Oxfordshire Osteoporosis Service in 1995. John Wass is currently the Clinical Reference Group Chair for Endocrinology in the UK. He was President of the European Federation of Endocrine Societies from 2001-2203 and was Chairman of the Society for Endocrinology (2006-2009). He was awarded the Distinguished Physician of the Year Award by the American Endocrine Society, the first non-American to ever receive this award Elected Academic Vice President of the Royal College of Physicians London in 2012 he has chaired the Royal College of Physicians Working Party 'Action on Obesity: Comprehensive Care for All' published in January 2013. Wiebke Arlt qualified at the University of Cologne in 1990. She trained in Endocrinology from 1994 to 1998 under the auspices of Professor Bruno Allolio at the University Hospital Würzburg, Germany. She then spent two years in the Molecular Endocrinology Lab of the Department of Paediatrics at the University of California in San Francisco (UCSF), hosted by Walter Miller. Following her return to Wuerzburg in 2001 she was appointed Consultant Endocrinologist. She obtained a prestigious Heisenberg Fellowship from the German Research Council and moved to Birmingham in October 2002. In 2004, she obtained an MRC Senior Clinical Fellowship and was appointed Senior Lecturer at the University of Birmingham. Promotion to Chair of Medicine in 2006 and to Head of the Centre for Endocrinology, Diabetes and Metabolism in 2008. She was awarded the William Withering Chair of Medicine in 2014 and appointed as Director of the newly founded Institute of Metabolism and Systems Research in 2015. Professor Semple is an endocrinologist based at the University of Edinburgh, where he is also Dean of Postgraduate Research for the College of Medicine and Veterinary Medicine. His interests include insulin resistance, diabetes, hypoglycaemia and mosaic growth disorders, in each of which he engages in fundamental molecular and cellular research, translational studies, and clinical practice.

Fully comprehensive evidence-based and highly valued reference work Contains wide-ranging and pragmatic advice on diagnosis, with clear guidelines for recommended management, while also covering the underlying scientific principles 15 overarching sections, with new sections on Endocrinology of Pregnancy and Management of the Transgender Patient included Over 800 images complementing the extensive text and information provided Includes full access to the online edition of the textbook