PART ONE: An Introduction to the Study of Organic Chemistry 1. Remembering General Chemistry: Electronic Structure and Bonding 2. Acids and Bases: Central to Understanding Organic Chemistry TUTORIAL: Acids and Bases 3. An Introduction to Organic Compounds: Nomenclature, Physical Properties, and Structure PART TWO: Electrophilic Addition Reactions, Stereochemistry, and Electron Delocalization TUTORIAL: Using Molecular Models 4. Isomers: The Arrangement of Atoms in Space TUTORIAL: Interconverting Structural Representations 5. Alkenes: Structure, Nomenclature, and an Introduction to Reactivity • Thermodynamics and Kinetics TUTORIAL: Drawing Curved Arrows 6. The Reactions of Alkenes • The Stereochemistry of Addition Reactions 7. The Reactions of Alkynes • An Introduction to Multistep Synthesis 8. Delocalized Electrons: Their Effect on Stability, pKa, and the Products of a Reaction • Aromaticity and Electronic Effects: An Introduction the Reactions of Benzene TUTORIAL: Drawing Resonance Contributors PART THREE: Substitution and Elimination Reactions 9. Substitution and Elimination Reactions of Alkyl Halides 10. Reactions of Alcohols, Ethers, Epoxides, Amines, and Sulfur-Containing Compounds 11. Organometallic Compounds 12. Radicals TUTORIAL: Drawing Curved Arrows in Radical Systems PART FOUR: Identification of Organic Compounds 13. Mass Spectrometry; Infrared Spectroscopy; and UV/Vis Spectroscopy 14. NMR Spectroscopy PART FIVE: Carbonyl Compounds 15. Reactions of Carboxylic Acids and Carboxylic Acid Derivatives 16. Reactions of Aldehydes and Ketones • More Reactions of Carboxylic Acid Derivatives 17. Reactions at the α-Carbon TUTORIAL: Synthesis and Retrosynthetic Analysis PART SIX: Aromatic Compounds 18. Reactions of Benzene And Substituted Benzenes 19. More About Amines • Reactions of Heterocyclic Compounds PART SEVEN: Bioorganic Compounds 20. The Organic Chemistry Of Carbohydrates 21. Amino Acids, Peptides, and Proteins 22. Catalysis in Organic Reactions and in Enzymatic Reactions 23. The Organic Chemistry of the Coenzymes, Compounds Derived from Vitamins 24. The Organic Chemistry of the Metabolic Pathways 25.  The Organic Chemistry of Lipids 26. The Chemistry of the Nucleic Acids PART EIGHT: Special Topics in Organic Chemistry 27. Synthetic Polymers 28. Pericyclic Reactions Appendix I  – pKa Values Appendix II  – Kinetics Appendix III  – Summary of Methods Used to Synthesize a Particular Functional Group Appendix IV  – Summary of Methods Employed to Form Carbon-Carbon Bonds Appendix V   – Spectroscopy Tables Appendix VI  – Physical Properties of Organic Compounds Appendix VII – Answers to Selected Problems

A modern, streamlined organisation emphasises unifying principles of reactivity, offering an economy of presentation and discouraging memorisation The text consistently highlights the fundamental reason for all chemical reactions – electrophiles combine with nucleophiles — in order to keep students focused on the key ideas. Students are introduced to synthetic and retrosynthetic chemistry early on, allowing them to grasp multistep synthesis from the beginning.   The textbook bridges the gap between organic chemistry and biochemistry Because bioorganic chemistry is the bridge between organic chemistry and biochemistry, the text emphasises that the organic reactions that chemists carry out in the laboratory are similar to those performed by nature inside a cell. These connections are especially important to biological science majors. In Chapters 1-20, the bioorganic material is presented as “interest boxes” and within the last sections of the chapters so that this material is available to the student without requiring the instructor to introduce bioorganic topics into the course. Chapters 21—26 focus on the organic chemistry of living systems. These chapters have the unique distinction of containing more chemistry than is typically found in the corresponding parts of a biochemistry text. Chapter 21   Amino Acids, Peptides, And Proteins Chapter 22   Catalysis In Organic Reactions And In Enzymatic Chapter 23   The Organic Mechanisms Of The Coenzymes, Compounds Derived From Vitamins Chapter 24   The Organic Chemistry Of The Metabolic Pathways Chapter 25   The Organic Chemistry Of Lipids Chapter 26   The Chemistry Of The Nucleic Acids   NEW! Improved visuals and organisation engage students with difficult subject matter, organises the chapter content and improves ease of use: NEW! Expanded annotations reinforce the revised art program and help keep students focused on the most important material.  NEW! Numerous subheads are part of a redesigned text that enhances ease of use and gives the text a modern look and feel. Subheads help students locate important topics, show how that content develops within the section, and break the presentation into “bite-sized” portions that are easier to comprehend and connect.   Strengthened emphasis on the strategies needed to solve problems and master the content Passages explaining important problem-solving strategies — content the student must learn — are clearly labeled with a LEARN THE STRATEGY label. Follow-up problems that require students to apply the just learned strategy are labeled with a USE THE STRATEGY label. These labels, which are implemented throughout the entire text, allow students to easily find important content and practice its use.     NEW and UPDATED! New and restructured features give students additional conceptual and skill building support UPDATED! Tutorial spreads and Design a Synthesis sections explicitly highlight essential skills. NEW! Marginal notes highlighting relative reactivity and the Organising What We Know feature now align with each other to better relate skill building to conceptual understanding. Newly highlighted Problem-Solving Strategies guide students on how to approach various problems and help to develop critical thinking skills.

About the Book   The textbook bridges the gap between organic chemistry and biochemistry Because bioorganic chemistry is the bridge between organic chemistry and biochemistry, the text emphasizes that the organic reactions that chemists carry out in the laboratory are similar to those performed by nature inside a cell. These connections are especially important to biological science majors. In Chapters 1-20, the bioorganic material is presented as “interest boxes” and within the last sections of the chapters so that this material is available to the student without requiring the instructor to introduce bioorganic topics into the course. Chapters 21—26 focus on the organic chemistry of living systems. These chapters have the unique distinction of containing more chemistry than is typically found in the corresponding parts of a biochemistry text. Chapter 21   Amino Acids, Peptides, And Proteins Chapter 22   Catalysis In Organic Reactions And In Enzymatic Chapter 23   The Organic Mechanisms Of The Coenzymes, Compounds Derived From Vitamins Chapter 24   The Organic Chemistry Of The Metabolic Pathways Chapter 25   The Organic Chemistry Of Lipids Chapter 26   The Chemistry Of The Nucleic Acids   UPDATED! Revised, accuracy-checked text provides increased exam relevancy To better prepare students for the MCAT exam, MCAT learning outcomes and MCAT-style questions have been added to the Student’s Study Guide and Solutions Manual, as well as MasteringChemistry. Contributing author Richard Morrison, University of Georgia, has reviewed and honed the problem solving presentations, end of chapter problems, and the solutions manual.   NEW! Improved visuals and organization engage students with difficult subject matter, organizes the chapter content and improves ease of use: Expanded annotations reinforce the revised art program and help keep students focused on the most important material. Numerous subheads are part of a redesigned text that enhances ease of use and gives the text a modern look and feel. Subheads help students locate important topics, show how that content develops within the section, and break the presentation into “bite-sized” portions that are easier to comprehend and connect.   Strengthened emphasis on the strategies needed to solve problems and master the content Passages explaining important problem-solving strategies — content the student must learn — are clearly labeled with a LEARN THE STRATEGY label. Follow-up problems that require students to apply the just learned strategy are labeled with a USE THE STRATEGY label. These labels, which are implemented throughout the entire text, allow students to easily find important content and practice its use.     NEW and UPDATED! New and restructured features give students additional conceptual and skill building support UPDATED! Tutorial spreads and Design a Synthesis sections explicitly highlight essential skills. NEW! Marginal notes highlighting relative reactivity and the Organizing What We Know feature now align with each other to better relate skill building to conceptual understanding. Newly highlighted Problem-Solving Strategies guide students on how to approach various problems and help to develop critical thinking skills. See more at: http://www.pearsonhighered.com/educator/product/Organic-Chemistry-Plus-MasteringChemistry-with-eText-Access-Card-Package/9780321803078.page#sthash.8kPWNcIB.dpuf